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SN/T 2179-2008 English PDF

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SN/T 2179-2008: Mammalian spermatogonial chromosome aberration test
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PDF similar to SN/T 2179-2008


Standard similar to SN/T 2179-2008

GB/T 25915.14   GB/T 25915.1   GB/T 25915.2   SN/T 2180   SN/T 2178   SN/T 2177   

Basic data

Standard ID SN/T 2179-2008 (SN/T2179-2008)
Description (Translated English) Mammalian spermatogonial chromosome aberration test
Sector / Industry Commodity Inspection Standard (Recommended)
Classification of Chinese Standard C70
Classification of International Standard 13.300
Word Count Estimation 6,622
Date of Issue 2008-09-04
Date of Implementation 2009-03-16
Quoted Standard GB 14924.1; GB 14925; Ministry of Health, "chemical toxicity identified technical specifications" (2005)
Adopted Standard OECD NO.483-1997, MOD
Issuing agency(ies) General Administration of Customs
Summary This standard specifies the mammalian spermatogonial chromosome aberration test terminology and definitions, test animals, test methods and the preparation and analysis of chromosome test data and reports. This standard is applicable to the detection of chemicals on the whole mammalian spermatogonial chromosome damage.

SN/T 2179-2008: Mammalian spermatogonial chromosome aberration test

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Mammalian spermatogonial chromosome aberration test Exit inspection and quarantine industry standard book People's Republic of China Mammalian spermatogonial chromosome aberration test Posted 2008-09-04 2009-03-16 implementation People's Republic of China The State Administration of Quality Supervision, Inspection and Quarantine released

Foreword

This revised standard adopts the United Nations Organisation for Economic Co-operation and Development (OECD) Chemicals Test Method No. 483 "mammalian spermatogonial cells Chromosome aberration test "(1997). This standard OECD Chemicals Test Method No. 483 compared with the following differences. --- To OECD Chemicals Test Method No. 483 were editorial changes; --- Increased the preamble; --- Increase the "preparation and analysis of chromosome" section. This standard was proposed by the State Administration of Quality Supervision Inspection and Quarantine of People's Republic of China. This standard by the National Certification and Accreditation Administration Committee. This standard is drafted by. People's Republic of China Tianjin Exit Inspection and Quarantine. Participated in the drafting of this standard. the Chemical Institute of Standardization, Jiangnan University, Tianjin Academy of Inspection and Quarantine Science and Technology. The main drafters. Zhang Yuan, Lu Gang, Zhao Zhuo, Zhao Qing, Li Xue Yang, Rui-chi in. This standard is the first release of the entry-exit inspection and quarantine industry standards. Mammalian spermatogonial chromosome aberration test

1 Scope

This standard specifies the mammalian spermatogonial chromosome aberration test terms and definitions, test animals, the test method and the preparation of chromosomes Analysis and test data and reports. This standard is applicable to the detection of chemical damage to the whole mammalian spermatogonial chromosome.

2 Normative references

The following documents contain provisions which, through reference in this standard and become the standard terms. For dated references, subsequent Amendments (not including errata content) or revisions do not apply to this standard, however, encourage the parties to the agreement are based on research Whether the latest versions of these documents. For undated reference documents, the latest versions apply to this standard. GB 14924.1 animal feed common quality standards GB 14925 Laboratory Animal Facilities and Environment The Ministry of Health "toxic chemicals identified technical specifications" (2005)

3 Terms and Definitions

The following terms and definitions apply to this standard. 3.1 Male gonadal germ cell meiosis haploid gametes after. 3.2 Structural chromosome damage, manifested as chromatid breaks or chromatid recombination fracture injury. 3.3 Chromosome structural damage, the performance of the two chromatids of the same sites are broken or appear to change the broken reorganization. 3.4 The length of the chromosome or chromatid damage is less than the width of a chromatid, arranged in the smallest error chromatids. 3.5 Chromosome number changes, unlike normal karyotype. 3.6 Normal diploid number of chromosomes in mammals, under the action of chemical mutagens, the number of triploid chromosome multiplied into four Times and the like. 3.7 Structural changes can be directly observed through the microscope to take place in the cell mitotic metaphase chromosomes. Such as chromosome deletions And fragments, a special dyeing conditions can be observed in the chromosome and swap exchange.

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