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GBZ85-2014 English PDF

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GBZ85-2014: Diagnosis of occupational acute dimethylformamide poisoning
Status: Valid

GBZ85: Evolution and historical versions

Standard ID	Contents [version]	USD	STEP2	[PDF] delivered in	Standard Title (Description)	Status	PDF
GBZ 85-2014	English	139	Add to Cart	3 days [Need to translate]	Diagnosis of occupational acute dimethylformamide poisoning	Valid	GBZ 85-2014
GBZ 85-2002	English	239	Add to Cart	2 days [Need to translate]	Diagnostic Criteria of Occupational Acute Dimethylformamide Poisoning	Obsolete	GBZ 85-2002

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Basic data

Standard ID	GBZ 85-2014 (GBZ85-2014)
Description (Translated English)	Diagnosis of occupational acute dimethylformamide poisoning
Sector / Industry	National Standard
Classification of Chinese Standard	C60
Classification of International Standard	13.100
Word Count Estimation	6,656
Date of Issue	10/13/2014
Date of Implementation	3/1/2015
Older Standard (superseded by this standard)	GBZ 85-2002
Quoted Standard	GBZ 51; GBZ 59; GBZ 71; GB/T 16180
Regulation (derived from)	State-Health-Communication [2014] 14
Issuing agency(ies)	National Health and Family Planning Commission
Summary	This standard specifies the occupational acute dimethylformamide poisoning diagnosis principles, diagnosis and classification principles. This standard applies to the diagnosis and treatment of occupational exposure to dimethylformamide caused acute poiso

GBZ85-2002: Diagnostic Criteria of Occupational Acute Dimethylformamide Poisoning

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Diagnostic Criteria of Occupational Acute Dimethylformamide Poisoning ICS 13.100 C60 GBZ People's Republic of China National Occupational Health Standards Diagnostic criteria for occupational acute dimethylformamide poisoning Released in.2002-04-08 2002-06-01 Implementation Issued by the Ministry of Health of the People's Republic of China

Foreword

Article 6.1 of this standard is recommended and the remainder is mandatory. According to the "People's Republic of China Occupational Disease Prevention Law" to develop this standard. Dimethylformamide is an industrially widely used organic solvent, with a greater exposure to dimethylformamide in occupational activities Acute poisoning occurs. In order to effectively control the acute dimethylformamide poisoning, protect the health of workers, the development of this standard. The development of this standard is in line with the occupation of acute chemical poisoning diagnosis of the general convergence, but also highlight the acute dimethyl Amide poisoning characteristics, and strive to fit the practical application of the principle of analysis at home and abroad nearly forty years, especially in the past decade Acute dimethylformamide poisoning on the basis of clinical research progress. Appendix A to this standard is an informative appendix. This standard is proposed and centralized by the Ministry of Health of the People's Republic of China. The standard responsible for the drafting unit. the Second Hospital of Shanxi Medical University, Shanghai Yangpu District Central Hospital; to participate in the drafting unit. Guangzhou City Occupational Disease Prevention and Control Hospital, Yuyao City, Zhejiang Province Health and Epidemic Prevention Station, Zhejiang Province, Fuyang City Health and Epidemic Prevention Station, Dongyang City, Zhejiang Province Health and Epidemic Prevention Station, Shanghai Occupational Disease Hospital, Zhejiang Center for Disease Control and Prevention, Heilongjiang Province, Labor and Health Occupational Disease Research By. This standard is interpreted by the Ministry of Health of the People's Republic of China. Diagnostic criteria for occupational acute dimethylformamide poisoning Occupational acute dimethylformamide poisoning refers to occupational activity. Short-term exposure to a large number of dimethyl formamide and cited From the liver to the main clinical manifestations of systemic disease.

1 Scope

This standard specifies the diagnostic criteria and principles of occupational acute dimethylformamide poisoning. This standard is applicable to the diagnosis and treatment of acute poisoning caused by occupational exposure to dimethylformamide. Non - occupational acute Dimethylformamide poisoning can also be used.

2 normative reference documents

The terms of the following documents are hereby incorporated by reference into this standard. Any date that references the date of the document All subsequent amendments (excluding corrigenda) or revisions do not apply to this standard, however, The parties to the agreement are able to use the latest version of these documents. Those who do not mind the date of the reference file, its latest The version applies to this standard. GBZ 51 Occupational chemical skin burns diagnostic criteria Diagnostic criteria for occupational toxic liver disease Identification of Occupational Injury and Occupational Disease Disability in Staff and Workers GB/T 16180.

3 diagnostic principles

According to the short term there is a large number of contact history of dimethyl formamide; liver damage-based clinical manifestations, and laboratory Check the results, combined with on-site labor hygiene survey, a comprehensive analysis and exclude other causes of similar diseases, Off.

4 contact reaction

Has one of the following a) after contact with dizziness, nausea, loss of appetite and other symptoms, no positive signs of the abdomen, laboratory tests no exception; b) contact with the skin, mucous membrane burning, pain, numbness and other symptoms.

5 Diagnostic and grading standards

5.1 mild poisoning Have one of the following a) performance in line with acute mild toxic liver disease (GBZ 51 in 4.ll); b) hemorrhagic gastroenteritis. 5.2 moderate poisoning Performance in line with acute moderate toxic liver disease (GBZ 51 in 4.l.2). 5.3 severe poisoning Performance in line with acute severe toxic liver disease (GBZ 51 in 4.l.2).

6 Principles of handling

6.1 Principles of treatment 6.1.1 from the scene, off the contaminated clothing, skin contamination immediately rinse with water. 6.1.2 no special detoxification drugs, the main protection of the liver, the treatment of hemorrhagic gastroenteritis and other symptomatic treatment. 6.1.3 severe poisoning can be applied adrenal glucocorticoid. 6.2 Other treatments 6.2.1 mild poisoning can be restored after the original work; moderate poisoning cured, the general should not engage in liver poison operations, severe After poisoning is cured. Should not engage in toxic operations. 6.2.2 For labor ability identification, according to GB/T 16180 treatment.

7 Correctly use the instructions in this standard

See Appendix A (informative).

Appendix A

(Informative) Correctly use the instructions in this standard A.1 Occupational exposure to dimethylformamide, can be absorbed through the respiratory tract and skin caused by poisoning, due to toxic routes and access Different contact volume, may have 6-24 hours of incubation period, so short-term exposure to large doses of contact with the performance of those who should be observed 24 hour. A.2 Occupational dimethylformamide poisoning clinical features, is the digestive system, especially liver damage, may have bleeding Sexual gastroenteritis, skin and mucous membrane irritation symptoms, direct contact can occur dermatitis or skin burns. A.3 This standard refers to bloody gastroenteritis, the clinical manifestations of light were nausea, vomiting, abdominal distension, abdominal pain, etc., of which abdominal pain Especially prominent. Severe cases of severe abdominal pain or colic, more in the upper abdomen and umbilical, but also throughout the abdomen, upper abdomen and umbilical Zhou has tenderness, no rebound pain and muscle tension. Laboratory can be seen dung blood test positive, fiber endoscopic visible gastroduodenal mucosa Congestion, edema, erosion, with bleeding. Hemorrhagic gastroenteritis is dimethylformamide poisoning when the more prominent performance, but according to the diagnosis, we should pay attention to other digestion Road disease phase identification. A.4 A small number of patients may appear proteinuria, blood urea nitrogen, creatinine increased, a transient blood pressure changes, ECG showed. rhythm Abnormal, I-II degree atrioventricular block and ST-T changes, short duration, good prognosis. So not as a diagnostic indicator, However, clinical treatment, we should pay attention to these changes. A.5 For ease of use, please refer to GBZ 51 for diagnostic grading and grading standards as follows. 4.1.l acute mild toxic liver disease. in a relatively short period of time to absorb higher concentrations of liver poison, the following performance Both, a. There are fatigue, loss of appetite, nausea, liver pain and other symptoms; b liver enlargement, soft, tender, may be associated with Mild yellow disease; c. Acute liver toxicity test for acute toxic liver disease. 4.1.2 acute moderate toxic liver disease. there is obvious fatigue, apathetic, anorexia, tired of oil, nausea, bloating, liver Area pain, etc., liver enlargement, tenderness obvious, acute toxic liver disease routine liver function test abnormalities, accompanied by the following performance One. a. Moderate jaundice; b spleen enlargement; c Course in more than four weeks. 4.1.3 acute severe toxic liver disease. in the above clinical manifestations, based on one of the following circumstances. a. Liver Encephalopathy; b. Obviously jaundice c. Ascites; d liver and kidney syndrome; Prothrombin time is prolonged at twice the normal value On, with bleeding tendency. Appendix C Clinical application of liver function test Acute toxic liver disease routine liver function test. refers to the serum alanine aminotransferase (ALT), serum bilirubin quantitative Test; if necessary, select the serum bile acid determination, serum aspartate aminotransferase (AST), serum prealbumin (PA) or serum glutathione (γ-GT) and so on. Appendix A3 jaundice classification Mild jaundice refers to serum bilirubin in normal, but less than 51.3mmol/L; moderate jaundice refers to serum total bilirubin in the 51.3-85.5 mmol/L between the obvious jaundice refers to the total serum bilirubin in 85.5mmol/L or more. A.6 urinary dimethyl formamide metabolites methyl formamide (NMF) and the concentration of dimethyl formamide in the air between Linear relationship, with specificity. Can be used as a biological monitoring exposure indicators. A.7 skin and mucous membrane contamination with water rinse, can not be washed with alkaline solution, in order to avoid dimethylamine. Skin burner press GBZ 51 treatment.

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