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GBZ25-2014 English PDF

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GBZ25-2014: Pathological diagnosis criteria of pneumoconioses
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GBZ 25-2014English399 Add to Cart 3 days [Need to translate] Pathological diagnosis criteria of pneumoconioses Valid GBZ 25-2014
GBZ 25-2002English359 Add to Cart 3 days [Need to translate] Pathologic Diagnostic Criteria of Pneumoconioses Obsolete GBZ 25-2002

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Basic data

Standard ID GBZ 25-2014 (GBZ25-2014)
Description (Translated English) Pathological diagnosis criteria of pneumoconioses
Sector / Industry National Standard
Classification of Chinese Standard C60
Classification of International Standard 13.100
Word Count Estimation 17,154
Date of Issue 10/13/2014
Date of Implementation 3/1/2015
Older Standard (superseded by this standard) GBZ 25-2002
Regulation (derived from) State-Health-Communication [2014] 14
Issuing agency(ies) National Health and Family Planning Commission
Summary This Standard specifies the principles of occupational pneumoconiosis pathological diagnosis and staging. This Standard applies to the pathological diagnosis "occupational classification and Directories" promulgated by the State in various provisions of p

GBZ25-2002: Pathologic Diagnostic Criteria of Pneumoconioses

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Pathologic Diagnostic Criteria of Pneumoconioses ICS 13.100 C60 GBZ People's Republic of China National Occupational Health Standards Pneumoconiosis diagnostic criteria Released in.2002-04-08 2002-06-01 Implementation Issued by the Ministry of Health of the People's Republic of China

Foreword

The entire contents of this standard are mandatory. According to the "People's Republic of China Occupational Disease Prevention Law" to develop this standard. Since the implementation of this standard date, the original standard GB 7883 -1988 inconsistent with this standard, subject to this standard. In the diagnosis of pneumoconiosis, often need to be a large specimen or autopsy specimens of the diagnosis. Must have standardized work Procedures and unified diagnostic criteria. So the development of this standard. Appendix A to this standard is an informative appendix, Appendix B, C, D, E is a normative appendix. This standard is proposed and centralized by the Ministry of Health of the People's Republic of China. This standard by the China Center for Disease Control and Prevention Occupational Health and Poison Control Institute and West China Medical University School of Public Health Responsible for drafting. Participate in the drafting of the unit Anshan Iron and Steel Institute of Labor and Health, Jiangxi Province, Labor and Occupational Disease Prevention and Control Institute, Shanghai Institute of Occupational Disease Prevention and Control. This standard is interpreted by the Ministry of Health of the People's Republic of China. Pneumoconiosis diagnostic criteria Pneumoconiosis refers to the production of activities inhalation of dust and the occurrence of lung fibrosis-based diseases.

1 Scope

This standard specifies the diagnostic criteria for pneumoconiosis. This standard applies to the pathology of pneumoconiosis.

2 diagnostic principles

According to detailed and reliable professional history and standardized inspection methods can be made by the results of pathological examination can make pneumoconiosis pathology diagnosis. Patients with X-ray, case summary or death and on-site labor hygiene information is a necessary reference for diagnosis.

3 Diagnostic and staging criteria

3.1 dust-free lungs Only see the lung and lung drainage area lymph node dust reaction; or lung and pulmonary drainage area lymph node pneumoconiosis, its Fan Circumcision and severity are not diagnosed as stage I pneumoconiosis. 3.2 Phase I pneumoconiosis a) the whole lung of the various aspects of the eye and mirror the total number of tuberculosis nodules in more than 20; or 10 or more, with nearly 1/1 Diffuse pulmonary fibrosis; b) diffuse diffuse pulmonary fibrosis grade 1/1 degree or more; c) full pneumoconiosis - emphysema area accounted for more than 50%. 3.3 Phase II pneumoconiosis a) the total number of lungs and microscopic examination of the total number of tuberculosis nodules in more than 50; or 20 or more, with 1/1 degrees Diffuse pulmonary fibrosis; b) diffuse diffuse pulmonary fibrosis grade 2/2 or more; c) full pneumoconiosis - emphysema area accounted for more than 75%. 3.4 Phase III pneumoconiosis a) the presence of dust in the lungs of massive fibrosis, and accompanied by more than I stage pneumonia disease basis; b) diffuse diffuse pulmonary fibrosis grade 3/3 degrees or more. Lesions in line with the above period a or b or c can make staging diagnosis.

4 Use this standard correctly

See Appendix A (informative), Appendix B, C, D, E (normative).

Appendix A

(Informative) Correctly use the instructions in this standard A.1 This standard applies only to the diagnosis of inorganic pneumoconiosis provided by the State and does not apply to the diagnosis of pulmonary diseases caused by organic dust; Only for autopsy and surgical lobectomy specimens, not for small pieces of lung biopsy, pulmonary drainage area lymph node biopsy, Lung puncture, lung lavage fluid and other specimens of pneumoconiosis pathological diagnosis. A.2 According to the People's Republic of China Ministry of Health (84) Wei Tong Zi No. 16, Chapter II of Article VII of the pathology professionals With pneumoconiosis pathological diagnosis. A.3 Pathological professionals with diagnostic rights After the "pneumoconiosis pathology examination application form" and the information provided by the inspection unit are available, Should immediately check and make a diagnosis report. Pneumoconiosis pathology report includes pneumoconiosis name, staging, pathological type and And disease. Pneumoconiosis pathological diagnosis report in duplicate, an archive, a delivery unit at the same level pneumoconiosis diagnosis group. pneumoconiosis Pathological diagnosis can be used as the basis for occupational disease treatment.

Appendix B

(Normative appendix) Pneumatic pathology standard notes B.1 Name of pneumoconiosis Named according to the name of the country's pneumoconiosis. B.2 pathology of pneumoconiosis B.2.1 nodular pneumoconiosis lesions to dust-based collagen fiber nodules, with other dust lesions exist. B.2.2 diffuse fibrosis of pneumoconiosis pneumoconiosis diffuse collagen fiber hyperplasia, with other dust lesions exist. B.2.3 dust-type pneumoconiosis lesions with dust spots with peritumoral emphysema-based changes, and other dust lesions exist. B.3 pneumoconiosis B.3.1 dust and pulmonary nodules eye view. the lesion was round, the state clear, gray color, touch a solid sense. Mirror. or for Silicon nodules, that is, with the core of the collagen fiber dust lesions; or mixed dust nodules, that is, collagen fibers and dust mixed, But the collagen fiber composition accounted for more than 50% of the lesions; or silicon nodules, that is, silicon nodules or mixed dust nodules and tuberculosis sexually transmitted diseases Change the formation of nodules. B.3.2 Dusty diffuse fibrosis Breathing bronchioles, alveoli, lobular septum, small bronchi and peripheral blood vessels, thoracic The diffuse collagen fiber hyperplasia due to dust deposition in the membrane area. B.3.3 dust spots eye. dark dark, soft, realm is not clear, with a diameter of 1.5 mm above the expansion of the air cavity (Peritumoral emphysema). Microscopic examination. lesions in the reticulite fiber, collagen fibers and dust mixed, collagen fiber composition less than 50%. Lesions and fibrosis of the lung interstitial was star-shaped, with peritumoral emphysema. B.3.4 dust block fibrosis eye view. the lesion is 2 × 2 × 2 cm above the gray black or black, tough texture of the fiber Clumps. Microscopic examination. or for the tubercle tuberculosis fusion or large dust collagen fibrosis or mixed for a variety of pneumoconiosis lesions. B.3.5 Dust response refers to lung, pleural, pulmonary drainage area lymph node dust deposition, macrophage response, mild fiber group Weaving and so on. B.4 the scope of pneumoconiosis and severity of the determination B.4.1 nodal count a) nodule diameter less than 2 mm, counted as 0.5 (mirror count); b) nodular diameter of 2 mm or more, counted as one (eye count, microscopic to determine); c) nodule diameter of 5mm or more, counted as two (eye count, microscopic to determine); d) nodular diameter of 10mm or more, counted as 3 (eye count, microscopic to determine). B.4.2 diffuse diffuse fibrosis (grade/degree) to determine a) l class lesions accounted for more than 25% of the whole lung area; b) 2 lesions accounted for more than 50% of the whole lung area; c) grade 3 lesions accounted for more than 75% of the whole lung area; d) 1 degree of fibrosis confined to the pulmonary lobules, or pulmonary lobular septum, small bronchi and small blood vessels around the dust fibrosis; e) 2 degrees on the basis of 1 degree, the fibrosis of the formation of each other connected to the grid or patchy, with limited hives change; f) 3 degree fibrosis damage most of the lung tissue or the formation of fiber mass; g) the severity of the lesion to determine the average of 20 slices prevail, such as the degree of emphasis on the level, to prevail. diagnosis Asbestos lung, we must see asbestos body. Asbestos lung complicated by the total area of the pleural plaque more than.200cm2 fat, pneumoconiosis lesions close to I Period or between I and II, can be diagnosed as I or II, respectively. B.4.3 Dust spot metering Mild dust area accounted for more than 25% of the lung area. Moderate dust area accounted for more than 50% of the whole lung area. Severe dust area accounts for more than 75% of the whole lung area. Pneumoconiosis area according to the results of all lungs to determine the eye, pleural surface dust spots included. B.5 pneumoconiosis and disease The following diseases are classified as pathogenesis of pneumoconiosis. B.5.1 Tuberculosis includes active tuberculosis, ie, cheese necrosis, caseous pneumonia, vacuolar tuberculosis, miliary Tuberculosis, bronchial endometrial tuberculosis, hilar lymph node tuberculosis and exudative tuberculous pleurisy. Diagnosis of stage III silicosis, Must have more than I stage of pneumoconiosis based on the same time with tuberculosis and tuberculosis lesions constitute the fibrous mass. B.5.2 Non-specific lung infections with severe bacteria, viruses and mycotic bronchitis, pneumonia and lung abscess, bronchiectasis Disease and so on. Difficult to distinguish inflammation caused by fibrosis and dust-induced fibrosis, can be used as a diffuse diffuse fibrosis diagnosis and Staging. B.5.3 Pulmonary heart disease, non-dust emphysema, pneumothorax. B.5.4 Lung cancer, malignant pleural mesothelioma. Appendix C. (Normative appendix) Pneumoconiosis specimen examination C.1 lung specimen fixation Autopsies should be carried out within 24 h after death. If frozen, its shelf life may be extended. According to the autopsy method to remove the lung, heart and mediastinum, immediately through the trachea to the lungs filled with 10% formalin solution, so that The lungs are swollen and fixed in physiological deep inspiration. Before the infusion of light the lungs of the leaves, excluding lung gas, remove tracheal endocrine To facilitate the liquid into the lungs Frozen, the formalin column about 40 cm high, slow drip. Perfusion rate of lung capacity Different, generally 1000 ~ 1500 ml, the liquid flow port position to move at any time, so that the lungs of the five lungs are appropriate to expand Swell. At the same time, the lungs should be placed in a spacious container containing 10% formalin, the lung surface with double wet gauze cloth Cover to prevent air dry. After all the five lobes swell, the trachea was ligated so that the leaves of the lungs were free to stretch in anatomical position. Fixed for five days According to the provisions of the cut inspection. C.2 eye inspection After the fixation of the lungs were placed on the lung plate, the lungs were placed on the back of the lungs, and the lungs were fixed to the plate on the left hand. Even as much as possible to make a large area of the lungs attached to the board. With a long knife to cut the lungs each piece of 1cm thick continuous coronal section. The trachea is long The incision of the incision is defined as 0-slice, and the lungs are cut into the majority of the abdomen (front) side and the back (rear) side, respectively. Before 3, before 2 ﹑ 1, 1, after 2, after 3. Observe the various aspects of the pneumoconiosis, such as dust spots, peritumoral lungs Swollen, nodular, diffuse fibrosis, massive fibrosis, lymph nodes and pleural lesions, etc., registered in the specified recording paper. Pathological diagnosis and staging of pneumoconiosis, pathological X-ray analysis, preservation and scientific research of pneumoconiosis Work, can provide useful information. Proposed conditional units are carried out as a check routine. C.3 Histology Each side of the lungs made of 10, must include the various lobes, each thick 3 ~ 4 mm, an area of 2 cm × 2 cm or so, drawn Tissue blocks include a variety of pneumoconiosis and suspected pneumoconiosis, including deep lung tissue and pleura. Draw the organization block number with Record table number is consistent. The number of lymph nodes is not limited. The number of tissue blocks for the diagnosis and onset of disease is not specified in 20 pieces within. Histological sections were stained with conventional paraffin sections and hematoxylin. Need to do when the reel fiber, plastic fiber, bombs Force fiber, tuberculosis, calcium, iron and other staining to identify the nature of the disease. C.4 analysis of lung dust Analyze the dust by the ashing method.

Appendix D

(Normative appendix) Application form, record form, report form D.1 pneumoconiosis pathology examination application form, three kinds of record form and report form format national unity. Where the application of pneumoconiosis pathology examination, must be completed by the entry of the standard application form, by the inspection unit and pneumoconiosis clinic Break unit contact. The diagnostic unit must complete the diagnostic work according to the record form and the report form format and requirements. D.2 pneumoconiosis pathology test application form D.3 records of pneumoconiosis pathology a. Pneumoconiosis specimen eye view record table; b. Evidence of pneumoconiosis lesions; c. Specimen records of pneumoconiosis specimens. D.4 pneumoconiosis pathological diagnosis report

Appendix E

Pneumoconiosis diagnostic criteria (Normative appendix) Pneumoconiosis diagnostic criteria with a set of 40 photos. The photographs show typical pneumoconiosis, which is the standard for pneumopathological diagnosis Auxiliary description of the provision.

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