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GB/T 24776-2009: Grouping and read-across methods of chemicals
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| Standard ID | Contents [version] | USD | STEP2 | [PDF] delivered in | Standard Title (Description) | Status | PDF |
| GB/T 24776-2009 | English | 229 |
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Grouping and read-across methods of chemicals
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GB/T 24776-2009
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Basic data | Standard ID | GB/T 24776-2009 (GB/T24776-2009) | | Description (Translated English) | Grouping and read-across methods of chemicals | | Sector / Industry | National Standard (Recommended) | | Classification of Chinese Standard | A80 | | Classification of International Standard | 13.300 | | Word Count Estimation | 10,165 | | Date of Issue | 2009-12-15 | | Date of Implementation | 2010-07-01 | | Regulation (derived from) | Announcement of Newly Approved National Standards No. 15 of 2009 | | Issuing agency(ies) | General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China, Standardization Administration of the People's Republic of China | | Summary | This standard specifies the chemical substances used for grouping test data gaps and cross- reference data predicting chemical endpoints guide. This standard applies to the use of grouping and cross- reference predicting the end of chemical substances missing data. | GB/T 24776-2009: Grouping and read-across methods of chemicals---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Grouping and read-across methods of chemicals
ICS 13.300
A80
National Standards of People's Republic of China
Chemical grouping and cross-reference method
Posted 2009-12-15
2010-07-01 implementation
Administration of Quality Supervision, Inspection and Quarantine of People's Republic of China
Standardization Administration of China released
Foreword
The standard reference of the United Nations' global chemical classification and labeling system "(GHS) and the first revision of the EU's" Chemicals Registration, Evaluation,
Authorisation and Restriction "(REACH) Guidance Document 3.2" information requirements and chemical safety assessment "(in English), and the relevant technical content
Said exactly the same file.
The Standard Appendix A, Appendix B is an informative annex.
This standard is managed by the National Standardization Technical Committee chemicals dangerous (SAC/TC251) and focal points.
This standard is drafted by. AQSIQ's import and export of chemical safety research center.
Participated in the drafting of this Standard. China Inspection and Quarantine Science Research Institute, the Chemical Institute of Standardization, Jiangsu CIQ,
Shandong Entry-Exit Inspection and Quarantine of Jiangxi.
The main drafters of this standard. Wang Lifeng, Falls Apart, Yu Wen Lin, Wang Xiaobing, Mei Jian, Zhou Xin, Sun Xin, Wang .
This standard is the first release.
Introduction
EU on June 1, 2007 through the registration of chemicals legislation, evaluation, authorization and restriction regulations (hereinafter referred to as the REACH Regulation),
And in 2008 June 1 formally implemented. After the implementation of the regulation of chemicals entering the EU market for unified management. Our country is
Response to the EU REACH regulations, developed a series of chemical safety standards equivalent to the conversion of the relevant technical content EU REACH regulations.
The standard reference of the United Nations' global chemical classification and labeling system "(GHS) and the first revision of the EU's" Chemicals Registration, Evaluation, Authorisation
And Restriction "(REACH) Guidance Document 3.2" information requirements and chemical safety assessment "(in English), its content and the relevant technical
Said exactly the same document, establish guidelines chemical grouping and cross-referenced.
Chemical grouping and cross-reference method
1 Scope
This standard gives a chemical substance use grouping and cross-reference guide Prediction chemicals end data of the test data gaps.
This standard applies to the use of grouping and cross-referencing method to predict the end of the data missing chemicals.
2 Terms and definitions
The following terms and definitions apply to this standard.
2.1
Further chemical same prediction method similar to the destination information to a structure based on endpoint information source chemicals.
2.2
A chemical class contains a similar structure or structural features of chemical substances, due to the structural similarities, their physicochemical
Characteristics, health or environmental toxicity Toxicity Characteristic features also have certain similarities, or according to certain rules change.
2.3
Material effects and molecular descriptors (quantitative) the relationship between the characters.
2.4
Characterized satisfy structural similarity, chemical substances for cross-referencing the target chemical substance.
2.5
Missing end point data, need to be predicted chemicals.
2.6
When the target chemical substances prediction, referred chemicals.
Heat 3 chemicals
3.1 Principle grouping
Process chemicals group, that is, having a similar chemical structure, the same time as having a similar chemical structure or similar
According to certain rules changes in the physical and chemical characteristics, health or environmental toxicity Toxicity Characteristic features of the process of a substance classified as chemical categories. will
Chemicals grouped after, can on the basis of cross-referencing.
Structural similarity 3.2
Structural similarity in the following areas.
a) The chemical substance having the same functional groups (such as aldehydes, epoxides, esters, metal ionic species specific);
b) each of the same chemical substance having the same component or classified as hazard class, having similar carbon chain length. This section mainly refers to
Unknown or variable component substances, complex reaction products or biological material substance (UVCB);
c) The chemicals in the structure (such as a carbon chain length) show an increasing or remain the same feature, this feature can be observed of
Physical and chemical properties of chemical substances (such as boiling range) to give;
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