HOME   Cart(4)   Quotation   About-Us Policy PDFs Standard-List
www.ChineseStandard.net Database: 189760 (18 Oct 2025)

GB/T 21753-2008 English PDF

US$169.00 ยท In stock
Delivery: <= 3 days. True-PDF full-copy in English will be manually translated and delivered via email.
GB/T 21753-2008: Chemicals -- Test method of repeated dose dermal toxicity: 21/28-day study
Status: Valid
Standard IDContents [version]USDSTEP2[PDF] delivered inStandard Title (Description)StatusPDF
GB/T 21753-2008English169 Add to Cart 3 days [Need to translate] Chemicals -- Test method of repeated dose dermal toxicity: 21/28-day study Valid GB/T 21753-2008

PDF similar to GB/T 21753-2008


Standard similar to GB/T 21753-2008

GB/T 21617   GB 23350   GB/T 21622   GB/T 21751   GB/T 21752   GB/T 21750   

Basic data

Standard ID GB/T 21753-2008 (GB/T21753-2008)
Description (Translated English) Chemicals -- Test method of repeated dose dermal toxicity: 21/28-day study
Sector / Industry National Standard (Recommended)
Classification of Chinese Standard A80
Classification of International Standard 13.300; 11.100
Word Count Estimation 7,733
Date of Issue 2008-05-12
Date of Implementation 2008-09-01
Adopted Standard OECD No.410-1981, IDT
Regulation (derived from) Announcement of Newly Approved National Standards No. 7, 2008 (No. 120 overall)
Issuing agency(ies) General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China, Standardization Administration of the People's Republic of China
Summary This standard specifies the chemical 21d/28d repeated dose dermal toxicity test scope, terms and definitions, test basic principles, test methods, test data and reports. This standard applies to detect short-term dermal toxicity of chemicals.

GB/T 21753-2008: Chemicals -- Test method of repeated dose dermal toxicity: 21/28-day study

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
. Chemicals Test method of repeated dose dermal toxicity. 21/28-day study ICS 13.300; 11.100 A80 National Standards of People's Republic of China Chemicals 21 days/28 day repeat dose dermal toxicity experiment method Posted 2008-05-12 2008-09-01 implementation Administration of Quality Supervision, Inspection and Quarantine of People's Republic of China Standardization Administration of China released

Foreword

This standard is identical with the Organisation for Economic Co-operation and Development (OECD) Chemicals testing guidelines No. 410 (1981), "21 days/28 day repeat Dose dermal toxicity test "(in English). The editorial changes made the following standard. --- Increasing the scope section; --- Change the unit of measure of legal units of measurement; --- Delete the reference section of the OECD. This standard is managed by the National Standardization Technical Committee chemicals dangerous (SAC/TC251) and focal points. This standard is drafted by. China Center for Disease Control and Prevention of Occupational Health and Poison Control. Participated in the drafting of this standard. Guangdong CIQ. The main drafters of this standard. Hou Fenxia, \u200b\u200bXuchong Hui, PAN Fang, Wu Jingwu. Chemicals 21 days/28 day repeat dose dermal toxicity experiment method

1 Scope

This standard specifies the chemical 21d/28d repeat dose dermal toxicity test scope, terms and definitions, basic principles of the test, the test Methods, test data and reports. This standard is applicable to the detection of short-term dermal toxicity of chemicals.

2 Terms and definitions

The following terms and definitions apply to this standard. 2.1 Means the amount of the amount of the test substance subjected, often mass (g, mg) or animals given per body weight of the test substance (mg/kg) is represented; e.g. The test was incorporated into the feed were fed infected, the test substance can also be used in the feed of a constant concentration (mg/kg) to represent. 2.2 It refers to several exposure dose not adversely effect the maximum exposure dose. It test animals per unit of body weight per day by an infected Sample of substance (mg/kg) is represented. 2.3 The test substance is exposed to repeated doses of harmful effects caused by exposure to repeated doses may be delayed exert toxic effects, increase the test substance or its agent Metabolite concentrations in susceptible tissue.

3 test basic principles

Animals were divided into several doses groups a dose animal percutaneous exposure per day, continuous exposure 21d/28d. Daily through percutaneous exposure Cheng observed toxicity performance. Death of animals during the test to be gross anatomy. After the end of the test surviving animals were sacrificed and dissected an examination. The main difference between 21d and 28d repeated percutaneous exposure test is different exposure period, the remaining points were similar in both tests can be shared A test method. Test Method 4 4.1 test animals 4.1.1 Selection of animal strains Can be used in adult rats, rabbits or guinea pigs, it can also be applied to other animals, but the need to explain the reasons. Start of the test animal body weight range should be. Rats 200g ~ 300g; rabbit 2.0kg ~ 3.0kg; guinea pigs 350g ~ 450g. When repeat dose dermal toxicity test as a long-term test Pre-tested, pre-test and test for a long-term use of the same strain of animals. 4.1.2 Number and Sex Each dose group to use at least 10 skin healthy animals (five female and five male), female infertility and should not move not pregnant

Tips & Frequently Asked Questions:

Question 1: How long will the true-PDF of GB/T 21753-2008_English be delivered?

Answer: Upon your order, we will start to translate GB/T 21753-2008_English as soon as possible, and keep you informed of the progress. The lead time is typically 1 ~ 3 working days. The lengthier the document the longer the lead time.

Question 2: Can I share the purchased PDF of GB/T 21753-2008_English with my colleagues?

Answer: Yes. The purchased PDF of GB/T 21753-2008_English will be deemed to be sold to your employer/organization who actually pays for it, including your colleagues and your employer's intranet.

Question 3: Does the price include tax/VAT?

Answer: Yes. Our tax invoice, downloaded/delivered in 9 seconds, includes all tax/VAT and complies with 100+ countries' tax regulations (tax exempted in 100+ countries) -- See Avoidance of Double Taxation Agreements (DTAs): List of DTAs signed between Singapore and 100+ countries

Question 4: Do you accept my currency other than USD?

Answer: Yes. If you need your currency to be printed on the invoice, please write an email to [email protected]. In 2 working-hours, we will create a special link for you to pay in any currencies. Otherwise, follow the normal steps: Add to Cart -- Checkout -- Select your currency to pay.