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Determination of L-hydroxyproline in foodstuffs for export. LC-MS/MS method
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SN/T 3929-2014
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Basic data Standard ID | SN/T 3929-2014 (SN/T3929-2014) | Description (Translated English) | Determination of L-hydroxyproline in foodstuffs for export. LC-MS/MS method | Sector / Industry | Commodity Inspection Standard (Recommended) | Classification of Chinese Standard | X04 | Classification of International Standard | 67.050 | Word Count Estimation | 20,242 | Date of Issue | 4/9/2014 | Date of Implementation | 11/1/2014 | Regulation (derived from) | State inspection certification (2014) 210 | Issuing agency(ies) | General Administration of Customs | Summary | This standard specifies the sample preparation HPLC food for export L- hydroxyproline and - mass spectrometry/mass spectrometry. This standard applies to liquid milk, milk powder, butter, yogurt, butter, cheese, chocolate, milk drinks and other milk and d |
SN/T 3929-2014: Determination of L-hydroxyproline in foodstuffs for export. LC-MS/MS method---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Determination of L-hydroxyproline in foodstuffs for export. LC-MS/MS method
People's Republic of China Entry-Exit Inspection and Quarantine Standards
Determination of food for export L- hydroxyproline
Liquid chromatography - mass spectrometry/mass spectrometry
LC-MS/MSmethod
Issued on. 2014-04-09
2014-11-01 implementation
People's Republic of China
The State Administration of Quality Supervision, Inspection and Quarantine released
Foreword
This standard was drafted in accordance with GB/T 1.1-2009 given rules.
Please note that some content of this document may involve patents, publication of this document
Institutions do not assume the responsibility to identify these patents.
This standard is proposed and managed by the National Certification and Accreditation Administration Committee.
This standard was drafted. China Inspection and Quarantine Science Research Institute, People's Republic of China Shanghai Exit Inspection and Quarantine, the People's Republic of China
Exit Inspection and Quarantine and the State Beijing.
The main drafters of this standard. Peng Tao, Deng Xiaojun, Zhu Ailing, Zhao Shanzhen, Li Xiaojuan, Wang Jinhua, Individual Students Chen Ying.
Determination of food for export L- hydroxyproline
Liquid chromatography - mass spectrometry/mass spectrometry
1 Scope
This standard specifies the sample preparation HPLC food for export L- hydroxyproline and - mass spectrometry/mass spectrometry.
This standard applies to liquid milk, milk powder, butter, yogurt, butter, cheese, chocolate, milk drinks and other milk and dairy products, protein powder of plant origin
Foods L- hydroxyproline liquid chromatography - mass spectrometry/mass spectrometry.
2 Method summary
Sample with concentrated hydrochloric acid hydrolysis at elevated temperature, diluted with water and freeze-dried, redissolved in acetonitrile extraction, graphitized carbon and purified hexane, collected
By liquid chromatography - mass spectrometry/mass spectrometry, internal standard.
3 Reagents and materials
Unless otherwise specified, use the analytical reagent, the water is deionized water.
3.1 acetonitrile. HPLC grade.
3.2 formic acid. HPLC grade.
3.3 Ammonium. HPLC grade.
3.4 hexane. HPLC grade.
3.5 hydrochloric acid. AR concentration of 12mol/L.
3.6 acetonitrile saturated with n-hexane. Take 100mL n-hexane (3.4), was added 50mL of acetonitrile (3.1), shaking after mixing, standing layered supernatant
spare.
3.7 6mol L hydrochloric acid solution /. Take 50mL hydrochloric acid (3.5) in 100mL volumetric flask, dilute to 100mL with water, set aside.
3.8 Mobile phase A. Weigh 0.158g ammonium formate (3.3) in 400mL of water was added 1mL formic acid (3.2), water to the
500mL, spare.
3.9 Mobile phase B. accurately taken mobile phase A (3.8) 25mL, 475mL acetonitrile mix, spare.
3.10 Standard substances. L- hydroxyproline (L-Hydroxyproline, CAS number. 51-35-4, purity of greater than 99%); 3,4-dehydro - Proline
(3,4-Didehydro-L-proline, CAS number. 4043-88-3 purity greater than 99%).
3.11 Standard stock solution. Weigh L- hydroxyproline (3.10) 10mg (accurate to 0.01mg), dissolved in water and dilute to 10mL
Brown volumetric flask to prepare a standard stock solution at a concentration of 1.0mg/mL of. 0 ℃ ~ 4 ℃ stored.
3.12 internal standard stock solution. Weigh 3,4 dehydrogenation - proline standard substance (3.10) 10mg (accurate to 0.01mg), dissolved in water
Brown and set the volume to 10mL volumetric flask, formulated at a concentration of 1.0mg/mL stock solution of the internal standard. 0 ℃ ~ 4 ℃ stored.
3.13 intermediate standard solution. precise amount of standard stock solution (3.11) 1mL, diluted with water and set the volume to 10mL brown volumetric flask with
Intermediate standard solution having a concentration of 100μg/mL of. 0 ℃ ~ 4 ℃ stored.
3.14 Internal standard solution. precise amount of internal standard stock solution (3.12) 1mL, diluted with water and set the volume to 10mL brown volumetric flask to prepare a
The concentration of the internal standard solution 100μg/mL of. 0 ℃ ~ 4 ℃ stored.
3.15 sea sand. pure chemistry, particle size 0.65mm ~ 0.85mm, SiO2 content of 99%.
3.16 graphitized carbon. SampliQcarbonSPEBulkSorbent, or equivalent person.
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