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GB/T 22252-2024: Determination of coenzyme Q10 in health foods
Status: Valid GB/T 22252: Evolution and historical versions
| Standard ID | Contents [version] | USD | STEP2 | [PDF] delivered in | Standard Title (Description) | Status | PDF |
| GB/T 22252-2024 | English | 199 |
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Determination of coenzyme Q10 in health foods
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GB/T 22252-2024
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| GB/T 22252-2008 | English | 139 |
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Determination of coenzyme Q10 in health food
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PDF similar to GB/T 22252-2024
Basic data | Standard ID | GB/T 22252-2024 (GB/T22252-2024) | | Description (Translated English) | Determination of coenzyme Q10 in health foods | | Sector / Industry | National Standard (Recommended) | | Classification of Chinese Standard | X83 | | Classification of International Standard | 67.050 | | Word Count Estimation | 10,120 | | Date of Issue | 2024-12-31 | | Date of Implementation | 2025-07-01 | | Older Standard (superseded by this standard) | GB/T 22252-2008 | | Issuing agency(ies) | State Administration for Market Regulation, China National Standardization Administration | GB/T 22252-2024: Determination of coenzyme Q10 in health foods---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
ICS 67.050
CCSX83
National Standard of the People's Republic of China
Replaces GB/T 22252-2008
Determination of Coenzyme Q10 in Health Food
Released on 2024-12-31
2025-07-01 Implementation
State Administration for Market Regulation
The National Standardization Administration issued
Foreword
This document is in accordance with the provisions of GB/T 1.1-2020 "Guidelines for standardization work Part 1.Structure and drafting rules for standardization documents"
Drafting.
This document specifies the technical requirements related to food quality. For food safety requirements, please refer to relevant laws, regulations, policies and food safety standards.
document.
This document replaces GB/T 22252-2008 "Determination of coenzyme Q10 in health foods". Compared with GB/T 22252-2008, except for the structure
In addition to adjustments and editorial changes, the main technical changes are as follows.
a) The scope of application has been changed (see Chapter 1, Chapter 1 of the.2008 edition);
b) The principle has been changed (see Chapter 4, Chapter 2 of the.2008 edition);
c) The preparation of standard solution has been changed (see 5.3, 3.7 and 3.8 of the.2008 edition);
d) Added sample preparation and sample handling (see 7.1 and 7.2);
e) The chromatographic reference conditions have been changed (see 7.3, 5.3 of the.2008 edition);
f) The detection limit and quantification limit have been changed (see Chapter 10, Chapter 1 of the.2008 edition);
g) The chromatogram has been changed (see Appendix A, Chapter 8 of the.2008 edition).
Please note that some of the contents of this document may involve patents. The issuing organization of this document does not assume the responsibility for identifying patents.
This document is proposed and coordinated by the National Technical Committee for Standardization of Special Foods (SAC/TC466).
This document was drafted by. China Light Industry Technology Innovation Center Co., Ltd., Anhui Food and Drug Inspection Institute, China Food Fermentation Industry Research Institute
Institute Co., Ltd., Zhejiang Xinweishi Biotechnology Co., Ltd., Tongfu International Holding Group Co., Ltd., Biostime (China) Co., Ltd., Tomson
By-Health Co., Ltd., Xianle Health Technology (Anhui) Co., Ltd., Wuhu Nuokang Biotechnology Co., Ltd., Hebei Chenguang Testing Technology
Service Co., Ltd., Stander Testing (Guangzhou) Co., Ltd., Fangyuan Mark Inspection and Testing (Shandong) Co., Ltd., Yantai New Era Health Industry
Ltd.
The main drafters of this document are. Wang Daobing, Wang Lingling, Zhong Qiding, Wu Zhuying, An Hongmei, Wang Jieqiong, Wu Yifan, Yue Hongwei, Ling Haiyuan,
Peng Yunying, Li Yong, Li Zhen, Peng Lishi, Gao Lan, Zhang Xiaofang, Qin Jingbo, Sheng Jianwei, Yin Lei, Zheng Minmin, Xiao Shucai, Zhong Shunhao, Wu Zhenzhi,
Zhou Baihua, Zhu Zhengjun, Zhao Kuihu, Ma Yuanyuan, Yan Lili, Yi Jiehan, and Yang Zuwei.
The previous versions of this document and the documents it replaces are as follows.
---First published in.2008 as GB/T 22252-2008;
---This is the first revision.
Determination of Coenzyme Q10 in Health Food
1 Scope
This document describes a method for the determination of coenzyme Q10 in health foods by HPLC.
This document is applicable to the determination of dosage forms such as tablets, hard capsules, soft capsules, granules, powders, oral liquids, and gel candies by high performance liquid chromatography.
Coenzyme Q10 in healthy food.
2 Normative references
The contents of the following documents constitute the essential clauses of this document through normative references in this document.
For referenced documents without a date, only the version corresponding to that date applies to this document; for referenced documents without a date, the latest version (including all amendments) applies to
This document.
GB/T 6682 Specifications and test methods for water used in analytical laboratories
3 Terms and definitions
There are no terms or definitions that require definition in this document.
4 Principle
The analytes in the sample were extracted with isopropanol or anhydrous ethanol, separated by reversed-phase high performance liquid chromatography, and detected by ultraviolet detector.
Qualitative, quantitative by external standard method.
5 Reagents
Unless otherwise specified, only chromatographic grade reagents were used.
5.1 Reagents
5.1.1 Water, GB/T 6682, Grade 1.
5.1.2 Methanol (CH4O).
5.1.3 Anhydrous ethanol (C2H6O).
5.1.4 Isopropyl alcohol (C3H8O).
5.2 Standard samples or standard substances
Coenzyme Q10 standard (C59H90O4, CAS No.. 303-98-0). purity not less than 98%, or nationally certified and certified standards
Sample or standard material.
5.3 Preparation of standard solution
5.3.1 Standard working solution A
5.3.1.1 Coenzyme Q10 standard stock solution A (500 μg/mL). Accurately weigh 25 mg of coenzyme Q10 standard (5.2) (accurate to
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