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Mammalian spermatogonial chromosome aberration test
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Basic data
| Standard ID | SN/T 2179-2008 (SN/T2179-2008) |
| Description (Translated English) | Mammalian spermatogonial chromosome aberration test |
| Sector / Industry | Commodity Inspection Standard (Recommended) |
| Classification of Chinese Standard | C70 |
| Classification of International Standard | 13.300 |
| Word Count Estimation | 6,628 |
| Date of Issue | 2008-09-04 |
| Date of Implementation | 2009-03-16 |
| Quoted Standard | GB 14924.1; GB 14925; Ministry of Health, "chemical toxicity identified technical specifications" (2005) |
| Adopted Standard | OECD NO.483-1997, MOD |
| Issuing agency(ies) | General Administration of Customs |
| Summary | This standard specifies the mammalian spermatogonial chromosome aberration test terminology and definitions, test animals, test methods and the preparation and analysis of chromosome test data and reports. This standard is applicable to the detection of chemicals on the whole mammalian spermatogonial chromosome damage. |
SN/T 2179-2008: Mammalian spermatogonial chromosome aberration test
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Mammalian spermatogonial chromosome aberration test
Exit inspection and quarantine industry standard book People's Republic of China
Mammalian spermatogonial chromosome aberration test
Posted 2008-09-04
2009-03-16 implementation
People's Republic of China
The State Administration of Quality Supervision, Inspection and Quarantine released
Foreword
This revised standard adopts the United Nations Organisation for Economic Co-operation and Development (OECD) Chemicals Test Method No. 483 "mammalian spermatogonial cells
Chromosome aberration test "(1997).
This standard OECD Chemicals Test Method No. 483 compared with the following differences.
--- To OECD Chemicals Test Method No. 483 were editorial changes;
--- Increased the preamble;
--- Increase the "preparation and analysis of chromosome" section.
This standard was proposed by the State Administration of Quality Supervision Inspection and Quarantine of People's Republic of China.
This standard by the National Certification and Accreditation Administration Committee.
This standard is drafted by. People's Republic of China Tianjin Exit Inspection and Quarantine.
Participated in the drafting of this standard. the Chemical Institute of Standardization, Jiangnan University, Tianjin Academy of Inspection and Quarantine Science and Technology.
The main drafters. Zhang Yuan, Lu Gang, Zhao Zhuo, Zhao Qing, Li Xue Yang, Rui-chi in.
This standard is the first release of the entry-exit inspection and quarantine industry standards.
Mammalian spermatogonial chromosome aberration test
1 Scope
This standard specifies the mammalian spermatogonial chromosome aberration test terms and definitions, test animals, the test method and the preparation of chromosomes
Analysis and test data and reports.
This standard is applicable to the detection of chemical damage to the whole mammalian spermatogonial chromosome.
2 Normative references
The following documents contain provisions which, through reference in this standard and become the standard terms. For dated references, subsequent
Amendments (not including errata content) or revisions do not apply to this standard, however, encourage the parties to the agreement are based on research
Whether the latest versions of these documents. For undated reference documents, the latest versions apply to this standard.
GB 14924.1 animal feed common quality standards
GB 14925 Laboratory Animal Facilities and Environment
The Ministry of Health "toxic chemicals identified technical specifications" (2005)
3 Terms and Definitions
The following terms and definitions apply to this standard.
3.1
Male gonadal germ cell meiosis haploid gametes after.
3.2
Structural chromosome damage, manifested as chromatid breaks or chromatid recombination fracture injury.
3.3
Chromosome structural damage, the performance of the two chromatids of the same sites are broken or appear to change the broken reorganization.
3.4
The length of the chromosome or chromatid damage is less than the width of a chromatid, arranged in the smallest error chromatids.
3.5
Chromosome number changes, unlike normal karyotype.
3.6
Normal diploid number of chromosomes in mammals, under the action of chemical mutagens, the number of triploid chromosome multiplied into four
Times and the like.
3.7
Structural changes can be directly observed through the microscope to take place in the cell mitotic metaphase chromosomes. Such as chromosome deletions
And fragments, a special dyeing conditions can be observed in the chromosome and swap exchange.
...
