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Mutation test method of reproductive cell for dangerous goods
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Basic data
| Standard ID | SN/T 2167-2008 (SN/T2167-2008) |
| Description (Translated English) | Mutation test method of reproductive cell for dangerous goods |
| Sector / Industry | Commodity Inspection Standard (Recommended) |
| Classification of Chinese Standard | C70 |
| Word Count Estimation | 6,616 |
| Date of Issue | 2008-09-04 |
| Date of Implementation | 2009-03-16 |
| Quoted Standard | GB 14924.1; GB 14925 |
| Adopted Standard | OECD NO.478-1984, MOD |
| Issuing agency(ies) | General Administration of Customs |
| Summary | This standard specifies the dangerous chemicals germ cell mutagenicity test methods and test results of the test and evaluation. This standard applies to hazardous chemicals Determination of germ cell mutagenicity. |
SN/T 2167-2008: Mutation test method of reproductive cell for dangerous goods
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Mutation test method of reproductive cell for dangerous goods
Exit inspection and quarantine industry standard book People's Republic of China
Dangerous germ cell mutagenicity
experiment method
Posted 2008-09-04
2009-03-16 implementation
People's Republic of China
The State Administration of Quality Supervision, Inspection and Quarantine released
Foreword
This revised standard adopts the United Nations Organisation for Economic Co-operation and Development (OECD) Chemicals Test Method No. 478 "Rodent dominant cause
Death Test "(1984).
This standard OECD Chemicals Test Method No. 478 compared with the following differences.
--- To OECD Chemicals Test Method No. 478 were editorial changes;
--- Increase the preamble.
This standard was proposed by the State Administration of Quality Supervision Inspection and Quarantine of People's Republic of China.
This standard by the National Certification and Accreditation Administration Committee.
This standard is drafted by. People's Republic of China Tianjin Exit Inspection and Quarantine.
Participated in the drafting of this standard. the Chemical Institute of Standardization, Jiangnan University, Tianjin Academy of Inspection and Quarantine Science and Technology.
The main drafters of this standard. Lining Tao, Zhang Yuan, Pang Zhen, Zhao Lihua, Zhao Zhuo, Li Xue Yang.
This standard is the first release of the entry-exit inspection and quarantine industry standards.
Dangerous germ cell mutagenicity
experiment method
1 Scope
This standard specifies the dangerous chemicals germ cell mutagenicity test methods and test results of the test and evaluation.
This standard applies to the determination of germ cell mutagenicity of hazardous chemicals.
2 Normative references
The following documents contain provisions which, through reference in this standard and become the standard terms. Any documents dated, its all subsequent repair
Change a single (not including errata content) or revisions do not apply to this standard, however, encourage the parties to study whether according to the agreement
You can use the latest versions of these documents. Undated document, the latest versions apply to this standard.
GB 14924.1 animal feed common quality standards
GB 14925 Laboratory Animal Facilities and Environment
3 Terms and Definitions
The following terms and definitions apply to this standard.
3.1
In the process of sperm occurred in ionizing radiation or toxic chemicals damage caused by chromosome breakage, a mutation of normal sperm and egg
Heterozygote combination after death occurs.
3.2
Complete shape, color red shiny, natural motion, after mechanical stimulation in sports response embryos.
3.3
Embryos smaller body, the shape is not complete, the placenta is small or insignificant embryo.
3.4
A complete embryo shape, body has been formed, smaller than normal embryos, dark color, no natural motion, no motor response to mechanical stimulation, the fetus
Disc small and pale embryos.
Test Method 4
4.1 Test equipment and reagents
4.1.1 Equipment
Gavage needles, syringes and needles, surgical scissors, scalpels, tweezers toothless.
4.1.2 Reagents
--- Distilled water, saline or a solvent such as dimethyl sulfoxide;
--- Available cyclophosphamide positive control, triethylene melamine, or ethyl methanesulfonate.
...