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Test method of acute inhalation toxicity for dangerous goods
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Basic data
| Standard ID | SN/T 2166-2008 (SN/T2166-2008) |
| Description (Translated English) | Test method of acute inhalation toxicity for dangerous goods |
| Sector / Industry | Commodity Inspection Standard (Recommended) |
| Classification of Chinese Standard | C70 |
| Classification of International Standard | 13.300 |
| Word Count Estimation | 6,648 |
| Date of Issue | 2008-09-04 |
| Date of Implementation | 2009-03-16 |
| Quoted Standard | GB 14924.1; GB 14925; GB 15193.3-2003; Ministry of Health, "chemical toxicity identified technical specifications" (2005); United Nations "on the Recommendations on the Transport of Dangerous Goods. Model Regulations " (fourteenth revised edition) |
| Adopted Standard | OECD NO.403-1981, MOD |
| Issuing agency(ies) | General Administration of Customs |
| Summary | This standard specifies the dangerous chemicals acute inhalation toxicity test equipment, testing equipment and reagents, test sample requirements, test animals, test procedures and test results. This standard applies to hazardous chemicals Determination of acute inhalation toxicity. |
SN/T 2166-2008: Test method of acute inhalation toxicity for dangerous goods
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Test method of acute inhalation toxicity for dangerous goods
Exit inspection and quarantine industry standard book People's Republic of China
DG acute inhalation toxicity test
Posted 2008-09-04
2009-03-16 implementation
People's Republic of China
The State Administration of Quality Supervision, Inspection and Quarantine released
Foreword
This revised standard adopts the United Nations Organisation for Economic Co-operation and Development (OECD) Chemicals Test Method No. 403 "acute inhalation toxicity test
Test "(1981).
This standard OECD Chemicals Test Method No. 403 compared with the following differences.
--- To OECD Chemicals Test Method No. 403 were editorial changes;
--- Increase the preamble.
This standard was proposed by the State Administration of Quality Supervision Inspection and Quarantine of People's Republic of China.
This standard by the National Certification and Accreditation Administration Committee.
This standard is drafted by. People's Republic of China Tianjin Exit Inspection and Quarantine.
Participated in the drafting of this standard. the Chemical Institute of Standardization, Jiangnan University, Tianjin Academy of Inspection and Quarantine Science and Technology.
The main drafters of this standard. Lining Tao, Zhang Yuan, Zhen Pang at Chi Rui, Zhao Zhuo, Zhang Jiangping.
This standard is the first release of the entry-exit inspection and quarantine industry standards.
DG acute inhalation toxicity test
1 Scope
This standard specifies the dangerous chemicals acute inhalation toxicity test test equipment, test equipment and reagents, test sample requirements, dynamic test
Substance, test procedures and test results.
This standard applies to the determination of the acute inhalation toxicity of hazardous chemicals.
2 Normative references
The following documents contain provisions which, through reference in this standard and become the standard terms. Any documents dated, its all subsequent repair
Change a single (not including errata content) or revisions do not apply to this standard, however, encourage the parties to study whether according to the agreement
You can use the latest versions of these documents. Undated document, the latest versions apply to this standard.
GB 14924.1 animal feed common quality standards
GB 14925 Laboratory Animal Facilities and Environment
GB 15193.3-2003 acute toxicity test
The Ministry of Health "toxic chemicals identified technical specifications" (2005)
United Nations "on the Recommendations on the Transport of Dangerous Goods Model Regulations ·" (fourteenth revised edition)
3 Terms and Definitions
United Nations "on the Recommendations on the Transport of Dangerous Goods Model Regulations ·" (fourteenth revised edition) as well as established the following terms and definitions apply
To this standard.
3.1
Oral, inhalation or contact with the skin may cause human death or serious injury, damage to human health of chemical substances.
3.2
So that the male and female adult rats after continuous inhalation 1h, the most likely cause of these test animals died within 14d half of vapor, mist or powder
Dust concentration.
4 Test Equipment
4.1-acting inhalation device
Acting inhalation test sites to ensure proper mechanical ventilation system to keep the air fresh inside exposed, the oxygen content of not less than 19% in the second
The carbon dioxide content of not more than 3%, the temperature is maintained within the range of 22 ℃ ± 2 ℃, relative humidity of 30% to 70%, air changes per hour three times ~
4, air speed should not be too large, exposed inside air is slightly negative pressure to prevent the test substance spill.
4.2 Static type inhalation device
And exposure time, determined according to animal species, the number of the container volume genera. The temperature was maintained in the range of 22 ℃ ± 2 ℃, relative humidity
30% to 70%.
5 Test equipment and reagents
5.1 Equipment
Acting or static inhalation exposure cabinet, Scales for animals.
...