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SN/T 3947-2014 English PDF

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SN/T 3947-2014: Chemical. Avian acute oral toxicity test
Status: Valid
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PDF similar to SN/T 3947-2014


Standard similar to SN/T 3947-2014

GB/T 35925   GB/T 4472   HG/T 3811   SN/T 2497.3   SN/T 3948   SN/T 3946   

Basic data

Standard ID SN/T 3947-2014 (SN/T3947-2014)
Description (Translated English) Chemical. Avian acute oral toxicity test
Sector / Industry Commodity Inspection Standard (Recommended)
Classification of Chinese Standard G09
Classification of International Standard 13.300
Word Count Estimation 16,186
Date of Issue 4/9/2014
Date of Implementation 11/1/2014
Quoted Standard GB/T 21757-2008
Regulation (derived from) State inspection certification (2014) 210
Issuing agency(ies) General Administration of Customs
Summary This standard specifies the test method of bird acute oral toxicity test, test procedures and data and reports. This standard applies to avian acute oral toxicity testing.

SN/T 3947-2014: Chemical. Avian acute oral toxicity test

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Chemical. Avian acute oral toxicity test People's Republic of China Entry-Exit Inspection and Quarantine Standards Chemicals Birds Acute oral toxicity test Issued on. 2014-04-09 2014-11-01 implementation People's Republic of China The State Administration of Quality Supervision, Inspection and Quarantine released

Foreword

This standard was drafted in accordance with GB/T 1.1-2009 given rules. This standard technical content and Organisation for Economic Co-operation and Development (OECD) Chemicals Test Method 223 "Birds Acute oral toxicity test" (Avianacuteoraltoxicitytest) (2010) identical in content. This standard is proposed and managed by the National Certification and Accreditation Administration Committee. This standard was drafted. People's Republic of China Shanghai Entry-Exit Inspection and Quarantine Bureau. The main drafters of this standard. Yao Lifang, Miao Wenbin, Li Chen, Chen Xiang, Jiang Wei, Li Wei, Zheng Hua, Zhu Hongkun, Cai Xiaofeng.

Introduction

Depending on the risk assessment project on the different information requirements, this standard provides three methods to choose from. --- Limited test. when is unlikely to happen less expected toxicity or death is often limited doses using this method. Dose limits shall apply For evaluation purposes, often 2000mg/kg. In addition to the control group, the test limit required 5 or 10 animals. --- LD50- slope test. In addition to assessing LD50 values, but also need to determine the dose - response curve slope and/or confidence intervals often used this method. The method has three to four stages, in addition to the control group, the test also take 24 or 34 animals. --- LD50 test. When you need only half the lethal dose, but not required to provide the dose - response curve slope and/or confidence intervals often used the method. The method has two stages, in addition to the control group, the test also requires 14 animals. Step Test Method Test points LD50- slope and LD50 test was. Chemicals Birds Acute oral toxicity test

1 Scope

This standard specifies the test method of bird acute oral toxicity test, test procedures and data and reports. This standard applies to avian acute oral toxicity testing.

2 Normative references

The following documents for the application of this document is essential. For dated references, only the dated version suitable for use herein Member. For undated references, the latest edition (including any amendments) applies to this document. GB/T 21757-2008 chemicals acute oral toxicity test Acute toxicity classification

3 Terms and Definitions

GB/T 21757-2008 define the following terms and definitions apply to this document. 3.1 Acute oral toxicity acuteoraltoxicity Test substance once or several times within 24h orally administered a dose of the harmful effects of the test animals caused. [GB/T 21757-2008, Definition 3.1] 3.2 Dose dose A given amount of the test substance, often mass (g, mg) or as mass per body weight of the subject animal of the test substance (mg/kg) is represented. [GB/T 21757-2008, the definition 3.3] 3.3 LD50 medianlethaloraldose; LD50 Disposable oral administration of the test substance is expected to cause 50% of the dose animal was dead, LD50 value per body weight in animals receiving test Quality material (mg/kg) to represent. [GB/T 21757-2008, the definition 3.5] 3.4 Limited doses limitdose The upper limit of the test dose (2000mg/kg or 5000mg/kg). [GB/T 21757-2008, the definition 3.6] 3.5 Probit probit method Is an abbreviation for probability integral conversion method, the basic principle is to change the dose logarithmic dose, the mortality rate will be converted into "probability unit", the A linear dose-response curve, the slope of the reciprocal of the standard deviation. Since the dose - response model probit dose-effect relationship as normal stars Cloth, standard normal distribution is symmetrical, therefore, the average value is the LD50 values. 3.6 The lowest dose value ldose The lowest dose of a phase value used. 3.7 The highest dose values hdose The highest dose used in the value of a stage.

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