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Determination of bacitracin zinc in feeds. High performance liquid chromatography
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NY/T 726-2003
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Basic data | Standard ID | NY/T 726-2003 (NY/T726-2003) | | Description (Translated English) | Determination of bacitracin zinc in feeds. High performance liquid chromatography | | Sector / Industry | Agriculture Industry Standard (Recommended) | | Classification of Chinese Standard | B20 | | Classification of International Standard | 65.120 | | Word Count Estimation | 6,640 | | Date of Issue | 2003-12-01 | | Date of Implementation | 2004-03-01 | | Adopted Standard | AOAC 65-1982, NEQ; AOAC 1168-1982, NEQ | | Summary | This standard specifies performance liquid chromatograph feed zinc bacitracin approach. This standard applies to pigs, chickens additive premix bacitracin zinc content. |
NY/T 726-2003: Determination of bacitracin zinc in feeds. High performance liquid chromatography ---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Determination of bacitracin zinc in feeds.High performance liquid chromatography
ICS 65.120
B20
People's Republic of China Agricultural Industry Standard
Determination of bacitracin zinc in feed
High performance liquid chromatography
Released on December 12,.2003
2004-03-01 implementation
Published by the Ministry of Agriculture
Foreword
This standard refers to AOAC65, 1168 (1982) "Method for determination of bacitracin in premix" and related domestic and foreign literature, combined with
The actual situation of our country was formulated.
Appendix A of this standard is a normative appendix.
This standard was proposed by the Ministry of Agriculture of the People's Republic
This standard is under the jurisdiction of the National Feed Industry Standardization Technical Committee.
This standard is drafted by the National Feed Quality Supervision and Inspection Center (Beijing).
The main drafters of this standard. Gao Sheng, Rao Zhenghua, Fan Li, Li Lizhen, Yang Yuming.
Determination of bacitracin zinc in feed
High performance liquid chromatography
1 Scope
This standard specifies the method for the determination of bacitracin zinc in feed by liquid chromatography.
This standard applies to the determination of zinc content of bacitracin in pig and chicken additive premixes.
2 Normative references
The terms in the following documents become the terms of this standard by reference to this standard. All dated references, followed by all
Modifications (not including errata content) or revisions do not apply to this standard, however, parties to agreements based on this standard are encouraged to study
Is it possible to use the latest version of these files? For undated references, the latest edition applies to this standard.
GB/T 6682 Analytical laboratory water specifications and test methods
GB/T 14699.1 Feed sampling method
3 Principle of the method
The bacitracin zinc in the additive premix can be extracted with an acidified organic solvent system, centrifuged, and the supernatant is taken for liquid chromatography analysis.
4 reagents and materials
The following reagents are of analytical grade unless otherwise specified, and the water meets the requirements of GB/T 6682 secondary water.
4.1 Phosphate buffer. pH 6.0, 1.5 g of dipotassium hydrogen phosphate and 8.5 g of potassium dihydrogen phosphate were weighed and dissolved in 1 L of water.
4.2 Phosphate-EDTA buffer. pH 4.5, weigh 13.6g potassium dihydrogen phosphate and 2.5g disodium edetate dissolved in 1L
In the water.
4.3 Bacitracin zinc standard solution.
4.3.1 Preparation of standard stock solution. Accurately weigh 150.0mg of bacitracin zinc standard, dissolve it with extraction solution, and make up to 100mL.
The solution bacillus zinc concentration was 1500 mg/L.
4.3.2 Intermediate solution. Pipette 10 mL of standard stock solution (4.3.1) and dilute to 50 mL with extraction solution. The concentration of the solution bacitracin zinc is
300mg/L.
4.3.3 Working solution. Pipette the intermediate solution (4.3.2) 0.20mL, 1.0mL, 5.0mL, and dilute to 10mL of the solution bacillus with the extraction solution.
The concentrations of the peptide zinc were 6 mg/L, 30 mg/L, and 150 mg/L, respectively.
4.4 Solvent system. Prepared according to Table 1. The volume of each solvent label is taken in a 100 mL volumetric flask and the volume is adjusted to the mark with water.
Table 1 solvent system table
Solvent
Volume/mL
A solution B solution extraction solution
Acetonitrile 0 40 28
Methanol 0 12 28
Phosphate-EDTA Buffer 20 20 0
Phosphate buffer 0 0 3
Concentrated phosphoric acid 0 0 1.2
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