HOME   Cart(0)   Quotation   About-Us Policy PDFs Standard-List
www.ChineseStandard.net Database: 189759 (19 Oct 2025)

GB 1903.6-2015 English PDF

US$279.00 · In stock
Delivery: <= 3 days. True-PDF full-copy in English will be manually translated and delivered via email.
GB 1903.6-2015: National food safety standard -- Food Nutrition Enhancer -- Vitamin E, Calcium succinate
Status: Valid
Standard IDContents [version]USDSTEP2[PDF] delivered inStandard Title (Description)StatusPDF
GB 1903.6-2015English279 Add to Cart 3 days [Need to translate] National food safety standard -- Food Nutrition Enhancer -- Vitamin E, Calcium succinate Valid GB 1903.6-2015

PDF similar to GB 1903.6-2015


Standard similar to GB 1903.6-2015

GB 1886.98   GB 1886.74   GB 1886.40   GB 1903.15   GB 1903.5   GB 1903.14   

Basic data

Standard ID GB 1903.6-2015 (GB1903.6-2015)
Description (Translated English) National food safety standard -- Food Nutrition Enhancer -- Vitamin E, Calcium succinate
Sector / Industry National Standard
Classification of Chinese Standard X40
Word Count Estimation 13,140
Date of Issue 2015-11-13
Date of Implementation 2016-05-13
Regulation (derived from) National Health and Family Planning Commission Announcement No
Issuing agency(ies) National Health and Family Planning Commission of the People's Republic of China, State Food and Drug Administration

GB 1903.6-2015: National food safety standard -- Food Nutrition Enhancer -- Vitamin E, Calcium succinate


---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
(National food safety standards of food nutrition fortifier Calcium vitamin E succinate) National Standards of People's Republic of China National Food Safety Standard Food nutrition fortifier Calcium Vitamin E succinate Issued on. 2015-11-13 2016-05-13 implementation People's Republic of China National Health and Family Planning Commission released National Food Safety Standard Food nutrition fortifier Calcium Vitamin E succinate

1 Scope

This standard applies to vitamin E (d-α- tocopherol) and succinic anhydride for esterification, food and nutrition and then with calcium to form strong Vitamin E succinate calcium agent. 2 molecular formula, relative molecular mass and structural formula Formula 2.1 C66H106CaO10 2.2 formula 2.3 relative molecular mass 1099.64 (according to 2011 international relative atomic mass)

3 Technical requirements

3.1 Sensory requirements Sensory requirements shall comply with the requirements of Table 1. Table 1 Sensory requirements Project requires test methods Color white to pale yellow Status granular powder, unbonded The appropriate amount of sample is placed in a clean, dry white porcelain dish, under natural light, observed Color and status 3.2 Physical and Chemical Indicators Physical and chemical indicators should be consistent with the provisions of Table 2. Table 2. Physical and chemical indicators Item Index Test Method Vitamin E succinate calcium content (dry basis), w /% 96.0 ~ 102.0 Appendix A A.4 Alkalinity comply with Appendix A A.5 Absorbance, E1 m (286nm) 36.0 ~ 40.0 A.6 in Appendix A Loss on drying, w /% ≤ 2.0 Appendix A A.7 α- tocopherol, w /% ≤ 0.5 Appendix A A.8 Chloride (Cl dollars), w /% ≤ 0.212 A.9 in Appendix A Specific rotation, [α] D20 ℃/[(°) · dm2 · kg-1] ≥ 24.0 Appendix A A.10 Arsenic (As)/(mg/kg) ≤ 2.0 GB 5009.76 Lead (Pb)/(mg/kg) ≤ 2.0 GB 5009.12

Appendix A

Testing method A.1 Safety Tips Reagents The standard test methods used for toxic or corrosive, care should be taken. As splashed on the skin should stand That is rinsed with water, severe cases should be treated immediately. When using a volatile acid, it should be carried out in a fume hood. A.2 General Provisions Unless otherwise specified in this standard, the use of analytical reagent purity should be more than the standard titration solution, standard solution for measuring impurities, Preparations and products, should be GB/T 601, GB/T 602, the provisions of GB/T 603 preparation, test water should be consistent with GB/T 6682-2008 in Three water regulations. Solution was used in the tests did not indicate what is formulated with solvent, it refers to an aqueous solution. A.3 Identification Test A.3.1 nitric acid color reaction A.3.1.1 Reagents and materials A.3.1.1.1 acetic acid. A.3.1.1.2 ethanol. A.3.1.1.3 nitrate. A.3.1.2 analysis step Weigh the sample 0.05g, add 1mL of acetic acid dissolved, add ethanol 9mL when mixed with 2mL nitric acid, 75 ℃ water bath 15min. Light red to orange solution was presented. A.3.2 qualitative calcium reaction A.3.2.1 Reagents and materials A.3.2.1.1 chloroform. A.3.2.1.2 hydrochloric acid. 36% to 38%. A.3.2.1.3 ammonia. 25% to 28%. A.3.2.1.4 ammonium carbonate. A.3.2.1.5 ammonium oxalate (C2H8N2O4 · H2O). A.3.2.1.6 potassium chromate. A.3.2.1.7 acetic acid. A.3.2.1.8 10% aqueous ammonia. amount of 400mL ammonia (A.3.2.1.3) diluted with water to 1000mL. A.3.2.1.9 ammonium carbonate solution. Weigh 20g of ammonium carbonate, plus 20mL10% dissolved ammonia, diluted with water to 100mL. A.3.2.1.10 ammonium oxalate solution. Weigh 3.5g of ammonium oxalate, dissolved in water and diluted to 100mL. A.3.2.1.11 Potassium chromate solution. Weigh 10g potassium chromate, dissolved in water and diluted to 100mL. A.3.2.2 analysis step A.3.2.2.1 Weigh the sample 5g, chloroform was added to dissolve 30mL, plus 10mL hydrochloric acid, mixed with shaking and allowed to stand 10min. Water points Meet 5mL, 10% aqueous ammonia and, as the test solution and the solution of calcium a qualitative response. A.3.2.2.2 take platinum wire, with hydrochloric acid wet, dipped in the above test solution, colorless alcohol lamp burning in the flame, the flame that was brick red. A.3.2.2.3 test solution 1mL taken in a test tube, adding ammonium carbonate solution, a white precipitate. A.3.2.2.4 take the test solution 1mL in a test tube, add ammonium oxalate solution, a white precipitate; plus acid insoluble precipitate, plus hydrochloric acid Shen Precipitate dissolved. A.3.2.2.5 take the test solution 1mL in a test tube, add 10 drops of potassium chromate solution, the heating does not produce precipitation. A.3.3 IR Weigh pre-dried (drying method, see A.7) after sample 0.08g, was added 0.2mL of carbon tetrachloride was dissolved in the solution by Test GB/T 6040 liquid film method, and standard spectra comparison. IR spectrum shown in Figure B.1. A.4 Determination of calcium content of vitamin E succinate A.4.1 Method summary Vitamin E succinate in the role of calcium acetate, methyl vitamin E succinate, and then by high-performance liquid chromatography, external standard method Calculation of vitamin E succinate and calcium content. A.4.2 Reagents and materials A.4.2.1 ethanol. A.4.2.2 acetic acid. A.4.2.3 methanol. A.4.2.4 vitamin E succinate standards (TocopherolacidSuccinate, CAS. 4345-03-3). A.4.2.5 α- tocopherol standards (AlphaTocopherol, CAS. 10191-41-0). A.4.2.6 acetic acid solution. 15. A.4.2.7 ethanol - acetic acid. 9 parts ethanol and 1 part of acetic acid solution (A.4.2.6) mixture. A.4.3 Instruments and Equipment High performance liquid chromatograph. with UV detection, or other equivalent detectors. A.4.4 reference chromatographic conditions A.4.4.1 Column. C18 column, 4.6mm × 250mm, particle size 5μm. A.4.4.2 Mobile phase. methanol. water. acetic acid = 97.2.1. A.4.4.3 Column temperature. 30 ℃. A.4.4.4 flow rate. 2.2mL/min. A.4.4.5 detection wavelength. 284nm. A.4.4.6 Injection volume. 20μL. A.4.5 Analysis step A.4.5.1 Preparation of standard solutions Weigh vitamin E succinate standard 50mg (accurate to 0.0001g), with ethanol - acetic acid dissolved solution (A.4.2.7) and a constant volume To 50mL, shake, as the standard solution. The standard solution containing 1mg per milliliter of vitamin E succinate. A.4.5.2 Preparation of sample solution Weigh pre-dried (drying methods, see A.7) samples 50mg (accurate to 0.0001g), with ethanol - acetic acid dissolved solution (A.4.2.7) And set the volume to 50mL, shake, as the sample solution. A.4.5.3 system suitability test Weigh vitamin E succinate standards 50mg and α- tocopherol standard 50mg, with ethanol - acetic acid dissolved solution (A.4.2.7) And set the volume to 50mL, shake, as a mixed standard solution. The solution contains 1mg of vitamin E succinate and 1mg per milliliter α- tocopherol standard. A.4.4 using chromatographic conditions, multiple injections of mixed standard solution chromatography. Vitamin E succinate Esters and α- tocopherol separation should not be less than 2.0. Take a mixed solution of sample 5 consecutive times, the relative standard vitamin E succinate peak area Deviation of not more than 0.8%. A.4.5.4 Determination A.4.4 under chromatographic conditions, respectively standard solution and sample solution chromatography. According to the standard solution and the sample solution chromatogram FIG vitamin E succinate peak area, according to equation (A.1) calculates the sample of vitamin E succinate and calcium content. A.4.6 Calculation Results Vitamin E succinate calcium content mass fraction w1, according to equation (A.1) Calculated. w1 = ms mt × At As × 1099.6 1061.6 × 100% (A.1) Where. Ms --- Quality standard solution of vitamin E succinate, in milligrams (mg); Mt --- the quality of the sample, in milligrams (mg); At --- sample solution chromatogram vitamin E succinate peak area; As --- standard solution chromatogram vitamin E succinate peak area; 1099.6 --- vitamin E succinate calcium molar mass; 1061.6 --- vitamin E succinate molar mass. In two parallel determination results of the arithmetic average of the measurement results. Twice in the same condition absolutely independent determination results The difference is not more than 2% of the arithmetic mean. A.5 Determination of alkalinity A.5.1 Reagents and materials A.5.1.1 ether. A.5.1.2 hydrochloric acid. 36% to 38%. A.5.1.3 hydrochloric acid standard titration solution. c (HCl) = 0.1mol/L. A.5.1.4 phenolphthalein indicator solution. 10g/L. A.5.2 Analysis step Weigh the sample 0.20g, add 10mL ether, 2mL water, a few drops of phenolphthalein indicator solution 0.1mL and 0.1mol L solution of hydrochloric acid/shake uniform. The aqueous layer should be no red color. A.6 measured absorbance A.6.1 Reagents and materials Chloroform. A.6.2 Instruments and Equipment Spectrophotometer. A.6.3 Analysis step Weigh the sample 0.01g (accurate to 0.0001g), add chloroform to dissolve and dilute to 100mL, shake, as the sample solution. To take the Sample solution in 1cm cuvette with chloroform as blank using a spectrophotometer measured absorbance at 286nm wavelength. A.6.4 Calculation Results Absorbance E1 m (286nm) according to equation (A.2) Calculated. E1 m (286nm) = (A.2) Where. A --- The absorbance of the sample solution; M --- the quality of the sample, in grams (g). In two parallel determination results of the arithmetic average of the measurement results. Twice in the same condition absolutely independent determination results The difference is not more than 2% of the arithmetic mean. A.7 Determination of loss on drying A.7.1 Reagents and materials Phosphorus pentoxide. A.7.2 Instruments and Equipment Vacuum drying oven. A.7.3 Analysis step Accurately weighed sample 1g ~ 2g (accurate to 0.0001g) to constant weight aluminum weighing bottle, weigh the sample tile in the bottom of a thickness not Higher than 5mm. It means a vacuum oven over phosphorus pentoxide to make the desiccant, dried under reduced pressure at room temperature 24h. Remove the weighing bottle and weighed. repeat The above operation to constant weight. A.7.4 Calculation Results Loss on drying mass fraction w2 according to formula (A.3) Calculated. w2 = m1-m2 m × 100% (A.3) Where. m1 --- dried before weighing bottle and the sample mass, in grams (g); m2 --- quality, unit weighing bottle and dried sample in grams (g); M --- the quality of the sample, in grams (g). In two parallel determination results of the arithmetic average of the measurement results. Twice in the same condition absolutely independent determination results The difference is not more than 10% of the arithmetic mean. Determination A.8 α- tocopherol A.8.1 Reagents and materials With A.4.2. A.8.2 Instruments and Equipment With A.4.3. A.8.3 reference chromatographic conditions With A.4.4. A.8.4 Analysis step A.8.4.1 Preparation of standard solutions Weigh α- tocopherol standard 50mg ± 0.5mg, with ethanol - acetic acid dissolved solution (A.4.2.7) and set the volume to 100mL, shake. quasi- Indeed draw the solution 1.0mL in 100mL flask with ethanol - acetic acid dissolved solution (A.4.2.7) and diluted to the mark, shake, as standard solution. The standard solution at a concentration of 5mg/L. A.8.4.2 Preparation of sample solution Weigh the sample 100mg ± 0.5mg, with ethanol - acetic acid dissolved solution (A.4.2.7) and set the volume to 100mL, shake, as a sample Solution. A.8.4.3 system suitability test With A.4.5.3. A.8.4.4 Determination A.4.4 under chromatographic conditions, respectively standard solution and sample solution chromatography. Recording standard solution and the sample solution chromatogram FIG α- tocopherol peak area. A.8.5 results found The sample solution α- tocopherol peak area no larger than a standard solution peak area (ie sample α- tocopherol content of not more than 0.5%). A.9 chloride (Cl) Determination A.9.1 Reagents and materials A.9.1.1 acetic acid. A.9.1.2 ether. A.9.1.3 hydrochloric acid. 36% to 38%. A.9.1.4 nitrate. A.9.1.5 silver nitrate. A.9.1.6 hydrochloric acid standard titration solution. c (HCl) = 0.01mol/L. A.9.1.7 nitric acid solution. Take 105mL nitric acid, diluted with water to 1000mL, shake. A.9.1.8 silver nitrate solution. 0.1mol/L. A.9.2 Determination 0.10g sample was weighed out, added 4mL of acetic acid was dissolved, transferred to a separatory funnel, adding 20mL water and 50mL ether, thoroughly shaken, collected The aqueous phase in 50mL colorimetric tube; ether layer was again added 10mL of water, thoroughly shaken, the aqueous phase was collected and pooled. 6mL nitric acid solution was added, with Diluted with water to the mark, as the sample solution. Another 0.6mL0.01mol/L hydrochloric acid standard titration solution in 50mL colorimetric tube, add 6mL nitric acid solution was diluted with water to the mark, as the control solution. To the sample solution and control solution of silver nitrate were added 1.0mL Solution, shake for 5min in the dark. Colorimetric tube from above compare the turbidity of sample solution turbidity not deeper than the control solution, the sample Chloride content ≤0.212%. A.10 Determination of specific rotation A.10.1 Method summary By saponification then acidification vitamin E tocopherol succinate is converted to calcium was measured by optical rotation after n-heptane extraction. A.10.2 reagents and materials A.10.2.1 95% ethanol. A.10.2.2 sodium hydroxide. A.10.2.3 hydrochloric acid. 36% to 38%. A.10.2.4 n-heptane. A.10.2.5 ferricyanide. A.10.2.6 saturated solution of sodium hydroxide. A.10.2.7 sodium hydroxide solution. 0.2mol/L. A.10.2.8 hydrochloric acid solution. 11. A.10.2.9 10% potassium ferricyanide solution. take potassium ferricyanide 10.0g, sodium hydroxide solution (A.10.2.7) was shaken to dissolve and diluted to 100mL. A.10.2.10 phenolphthalein indicator solution. 10g/L. A.10.2.11 Erlenmeyer flask. A.10.2.12 reflux device. A.10.2.13 separating funnel. A.10.2.14 glass beads. A.10.3 instruments and equipment Instrument adopted GB/T 613 stipulated. A.10.4 Determination Weigh 0.5g (accurate to 0.0001g) sample in the conical flask, add 10mL95% ethanol, add a few grains of glass beads, a boiling water bath heating back flow. When boiling a solution, from the upper end of the return pipe is added 1mL of saturated sodium hydroxide solution, rinsed with a little water wall reflux, reflux 30min, Stop heating. Remove the conical flask, a few drops of phenolphthalein indicator solution with hydrochloric acid solution (A.10.2.8) carefully in hot pink and until it disappears, cold To room temperature. The solution was transferred to a separatory funnel, washed with a small amount of 95% ethanol conical flask, the combined solution was washed into a separatory funnel, then Add 25mL of n-heptane, stuffed with cork, shaking 1min, standing layer, discarding the lower solution. Add 10mL water to the separating funnel, stuffed bottle Stopper, shake and let stand until the layers separated, discarding the lower solution. Plus 10.0mL10% potassium ferricyanide solution to a separating funnel, stuffed with cork, shaking 45s, standing 30min stratification. Measured from the upper optical rotation method according to GB/T 613 stipulated. A.10.5 Calculation Results Specific rotation value [α] 20 ℃ D with (°) · dm2 · kg-1 expressed by the formula (A.4) Calculated. [Α] 20 ℃ D = αV LXm × (1-D) × 0.783 (A.4) Where. Optical rotation α --- test solution, in degrees (°); The V --- volume of the solution was measured in milliliters (mL of); --- L of the measuring pipe length in decimeters (DM); X --- sample content of Vitamin E succinate calcium,%; M --- the quality of the sample, in grams (g); D --- Loss on drying,%; 0.783 --- α- tocopherol vitamin E succinate and calcium scaling factor, namely 861.42/1099.6. In two parallel determination results of the arithmetic average of the measurement results. Twice in the same condition absolutely independent determination results The difference is not more than 5% of the arithmetic mean.

Appendix B

Vitamin E succinate calcium standard infrared spectra Vitamin E succinate calcium standard infrared spectrum is shown in Figure B.1. Note. The spectra from the Japanese Pharmacopoeia (JPXⅥ, 2011). Figure B.1 vitamin E succinate calcium standard infrared spectra

Appendix C

Vitamin E succinate and α- tocopherol by high performance liquid chromatogram HPLC chromatograms of vitamin E succinate and α- tocopherol is shown in Figure C.1. Explanation. 1 --- vitamin E succinate; 2 --- α- tocopherol. Figure C.1 vitamin E succinate and α- tocopherol by high performance liquid chromatogram (1000mg/L)

Tips & Frequently Asked Questions:

Question 1: How long will the true-PDF of GB 1903.6-2015_English be delivered?

Answer: Upon your order, we will start to translate GB 1903.6-2015_English as soon as possible, and keep you informed of the progress. The lead time is typically 1 ~ 3 working days. The lengthier the document the longer the lead time.

Question 2: Can I share the purchased PDF of GB 1903.6-2015_English with my colleagues?

Answer: Yes. The purchased PDF of GB 1903.6-2015_English will be deemed to be sold to your employer/organization who actually pays for it, including your colleagues and your employer's intranet.

Question 3: Does the price include tax/VAT?

Answer: Yes. Our tax invoice, downloaded/delivered in 9 seconds, includes all tax/VAT and complies with 100+ countries' tax regulations (tax exempted in 100+ countries) -- See Avoidance of Double Taxation Agreements (DTAs): List of DTAs signed between Singapore and 100+ countries

Question 4: Do you accept my currency other than USD?

Answer: Yes. If you need your currency to be printed on the invoice, please write an email to [email protected]. In 2 working-hours, we will create a special link for you to pay in any currencies. Otherwise, follow the normal steps: Add to Cart -- Checkout -- Select your currency to pay.