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GB 14922.2-2011 English PDF

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GB 14922.2-2011: Laboratory animal -- Microbiological standards and monitoring
Status: Obsolete

GB 14922.2: Evolution and historical versions

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GB 14922.2-2011English479 Add to Cart 3 days [Need to translate] Laboratory animal -- Microbiological standards and monitoring Obsolete GB 14922.2-2011
GB 14922.2-2001English359 Add to Cart 3 days [Need to translate] Laboratory animal -- Microbiological standards and monitoring Obsolete GB 14922.2-2001

PDF similar to GB 14922.2-2011


Standard similar to GB 14922.2-2011

GB/T 43051   GB/T 39760   GB/T 35823   GB 14925   GB 14923   GB 14922   

Basic data

Standard ID GB 14922.2-2011 (GB14922.2-2011)
Description (Translated English) Laboratory animal -- Microbiological standards and monitoring
Sector / Industry National Standard
Classification of Chinese Standard B44
Classification of International Standard 65.020.30
Word Count Estimation 12,172
Date of Issue 2011-06-16
Date of Implementation 2011-11-01
Older Standard (superseded by this standard) GB 14922.2-2001
Quoted Standard GB/T 14926.1; GB/T 14926.3; GB/T 14926.4; GB/T 14926.5; GB/T 14926.6; GB/T 14926.8; GB/T 14926.9; GB/T 14926.11; GB/T 14926.12; GB/T 14926.13; GB/T 14926.14; GB/T 14926.15; GB/T 14926.16; GB/T 14926.17; GB/T 14926.18; GB/T 14926.19; GB/T 14926.20; GB/T 14926.22; GB/T 14926.23; GB/T 14926.24; GB/T 14926.25; GB/T 14926.26; GB/T 14926.27; GB/T 14926.28; GB/T 14926.29; GB/T 14926.30; GB/T 14926.31; GB/T 14926.32; GB/T 14926.41; GB/T 14926.42; GB/T 14926.43; GB/T 14926.44; GB/T 14926.45; GB/T 14926.49; GB/T 14926.50; GB/T 14926.51; GB/T 14926.52; GB/T 14926.53; GB/T 14926.54; GB/T 14926.55; GB/T 14926.59; GB/T 14926.60; GB/T 14926.61; GB/T 14926.62; GB/T 14926.63; GB/T 14926.64; GB/T 14926.48; GB/T 14926.10; GB/T 14926.21; GB/T 14926.46; GB/T 14926.47; GB/T 14926.56; GB/T 14926.57;
Regulation (derived from) Announcement of Newly Approved National Standards No. 9 of 2011
Issuing agency(ies) General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China, Standardization Administration of the People's Republic of China
Summary This Chinese standard specifies grade and monitoring for microbiology laboratory animals. This standard applies to guinea pigs, hamsters, rabbits, dogs and monkeys, cleaning level and above in mice, rats.

GB 14922.2-2011: Laboratory animal -- Microbiological standards and monitoring

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Laboratory animal.Microbiological standards and monitoring ICS 65.020.30 B44 National Standards of People's Republic of China Replacing GB 14922.2-2001 Laboratory Animal Microbiology rating and monitoring Issued on. 2011-06-16 2011-11-01 implementation Administration of Quality Supervision, Inspection and Quarantine of People's Republic of China Standardization Administration of China released

Foreword

Of this Part 1, Chapter 2, Chapter 6 and Chapter 7 are recommended, the rest are mandatory. GB 14922 "animal" can be divided into the following two parts. --- GB 14922.1 "Laboratory Animal parasitology rating and monitoring"; --- GB 14922.2 "Microbiology Laboratory Animal rating and monitoring." This section GB 14922.2 "Microbiology Laboratory Animal rating and monitoring." This Part replaces GB 14922.2-2001 "Microbiology Laboratory Animal rating and monitoring." This section compared with GB 14922.2-2001, the main changes are as follows. a) Remove Listeria monocytogenes bacterium of the test items; b) experimental animals microbiological classification in terms of animal categories, the general level of animals, animal clean grade, specific pathogen free (SPF) animals and animal sterile level, increasing the corresponding abbreviation. This part of the National Standardization Technical Committee of experimental animals and focal points. This part of the National Standardization Technical Committee responsible for drafting the experimental animals. The main drafters of this section. Qiang Wei, contend, TIAN Ke-gong, Li, Huang Ren, Fan Wei, Qu Xiaqin. This section was first released in January 1994, the first revision in 2001. Laboratory Animal Microbiology rating and monitoring

1 Scope

GB 14922 of the provisions of this part of the microbiology laboratory animals and monitoring level. This section applies to guinea pigs, hamsters, rabbits, dogs and monkeys; clean and above mice, rats.

2 Normative references

The following documents contain provisions which, through reference in this section GB 14922, constitute provisions of this part. For dated references, All subsequent amendments (not including errata content) or revisions do not apply to this section, however, encourage the agreement on this section Whether the parties can study the latest versions of these documents. For undated reference documents, the latest versions apply to this section. GB/T 14926 (all parts) experimental animals

3 Terms and Definitions

The following terms and definitions apply to this part of GB 14922. 3.1 Common animal in conventional (CV) animal Do not carry specified zoonoses and animal pathogenic animal pathogens deadly infectious diseases. Referred to ordinary animals. 3.2 Clean Animal clean (CL) animal In addition to conventional animal pathogens should be excluded, the animals do not carry harmful interference Japanese scientific research large animal pathogens. simple He said clean animals. 3.3 Specific pathogen free animal specificpathogenfree (SPF) animal In addition to cleaning the animals should be excluded from the pathogen, but do not carry major potential pathogenic infections or conditions for scientific experiments and large interference pathogen experiments animal. Acronym SPF specific pathogen-free animal or animals. 3.4 Sterilizing grade animal germfree (GF) animal Laboratory animals no detectable all life forms. Referred to sterile animals.

4 animals Category

Press microbiological classification as follows. a) conventional animal; b) Clean Animal; c) specific pathogen free animal; d) sterilizing grade animals.

5 testing standards and indicators

5.1 Appearance Index Experimental animals should be healthy appearance, without exception. 5.2 Pathogen Index Pathogen indicators in Table 1, Table 2 and Table 3. 5.3 Indicators virus Virus indicators in Table 4, Table 5 and Table 6. Table 1 mice, rats pathogen detection project Animals Pathogen Level Animal species Mice and rats Salmonella Salmonellaspp. Yersinia pseudotuberculosis Yersiniapseudotuberculosis Yersinia enterocolitica Yersiniaenterocolitica Fungal skin disease original Pathogenicdermalfungi Beaded chain bacillus Streptobacillusmoniliformis Bronchial Bout bacillus Bordetellabronchiseptica Mycoplasma Mycoplasmaspp. Rat Corynebacterium Corynebacteriumkutscheri Tyzzer Tyzzer'sorganism Coli O115a, C, K (B) EscherichiacoliO115a, C, K (B) L. pneumophila bacterium Pasteurella Pasteurellapneumotropica Klebsiella pneumoniae Klebsiellapneumoniae Staphylococcus aureus Staphylococcusaureus Streptococcus pneumoniae Streptococcuspnemoniae Beta-hemolytic streptococcus β-hemolyticstreptococcus Pseudomonas aeruginosa Pseudomonasaeruginosa No bacteria can be found ● ● NOTE. ● You must test items required negative; ○ when necessary examinations, requiring negative. Table 2 guinea pig, hamster, rabbit pathogen detection project Animals Pathogen Level Animal species Hamster rabbit guinea pigs Salmonella Salmonellaspp. Yersinia pseudotuberculosis Yersiniapseudotuberculosis Yersinia enterocolitica Yersiniaenterocolitica Fungal skin disease original Pathogenicdermalfungi Beaded chain bacillus Streptobacillusmoniliformis Pasteurella multocida bacterium Pasteurellamultocida Bronchial Bout bacillus Bordetellabronchiseptica Tyzzer Tyzzer'sorganism L. pneumophila bacterium Pasteurella Pasteurellapneumotropica Klebsiella pneumoniae Klebsiellapneumoniae Staphylococcus aureus Staphylococcusaureus Streptococcus pneumoniae Streptococcuspnemoniae Beta-hemolytic streptococcus β-hemolyticstreptococcus Pseudomonas aeruginosa Pseudomonasaeruginosa No bacteria can be found ● ● ● NOTE. ● You must test items required negative; ○ when necessary examinations, requiring negative. Table 3 dogs, monkeys pathogen detection project Animals Pathogen Level Animal species Cynomolgus monkeys Salmonella Salmonellaspp. Fungal skin disease original Pathogenicdermalfungi Brucella Brucellaspp. Leptospira Leptospiraspp. Shigella Shigellaspp. Mycobacterium tuberculosis Mycobacteriumtuberculosis Leptospira aLeptospiraspp. Yersinia enterocolitica Yersiniaenterocolitica Campylobacter jejuni Campylobaceterjejuni NOTE. ● You must test items required negative; when necessary ○ test items required negative; when △ necessary test items, can be immune. It is not immune to a request negative. Table 4, mice, rats, virus detection project Animal Virus Level Animal species Mice and rats Lymphocytic choriomeningitis virus LymphocyticChoriomeningitisVirus (LCMV) Hantavirus Hantavirus (HV) Mouse pox virus EctromeliaVirus (Ect.) Mouse hepatitis virus MouseHepatitisVirus (MHV) Sendai virus SendaiVirus (SV) Mouse pneumonia virus PneumoniaVirusofMice (PVM) Reovirus type Ⅲ ReovirustypeⅢ (Reo-3) Mouse parvovirus MinuteVirusofMice (MVM) Mouse encephalomyelitis virus Theiler'sMouseEncephalomyelitisVirus (TMEV) Mouse adenovirus MouseAdenovirus (Mad) Polyomavirus PolyomaVirus (POLY) RV rat parvovirus strain RatParvovirus (KRV) Parvovirus H-1 rats Zhu RatParvovirus (H-1) Rat coronavirus/rat saliva lacrimal gland stomatitis virus RatCoronavirus (RCV)/SialodacryoadenitisVirus (SDAV) No virus can be found ● ● NOTE. ● You must test items required negative; ○ when necessary examinations, requiring negative. Table 5, guinea pig, hamster, rabbit virus detection project Animal Virus Level Animal species Hamster rabbit guinea pigs Lymphocytic choriomeningitis virus LymphocyticChoriomeningitisVirus (LCMV) Rabbit hemorrhagic disease virus RabbitHemorrhagicDiseaseVirus (RHDV) ● ● Sendai virus SendaiVirus (SV) Rabbit hemorrhagic disease virus aRabbitHemorrhagicDiseaseVirus (RHDV) ● ● Sendai virus SendaiVirus (SV) Mouse pneumonia virus PneumoniaVirusofMice (PVM) Reovirus type Ⅲ ReovirustypeⅢ (Reo-3) Rotavirus Rotavirus (RRV) No virus can be found ● ● ● NOTE. ● You must test items required negative; ▲ must test items can be immunized. It is not immune to a request negative. Table 6 dogs, a monkey virus detection project Animal Virus Level Animal species Cynomolgus monkeys Rabies virus RabiesVirus (RV) Canine parvovirus CanineParvovirus (CPV) Canine distemper virus CanineDistemperVirus (CDV) Infectious canine hepatitis virus InfectiousCanineHepatitisVirus (ICHV) Macaque herpesvirus 1 (B virus) CercopithecineHerpesvirusType1 (BV) Monkey reversal D-type virus SimianRetrovirusD (SRV) Simian immunodeficiency virus SimianImmunodeficiencyVirus (SIV) Monkey T-cell tropism virus type I SimianTLymphotropicVirusType1 (STLV-1) Monkeypox virus SimianPoxVirus (SPV) The four canines not immune to the virus ● NOTE. ● You must test items required negative; ▲ must test items require immunization.

6 tests

6.1 test animals should be in the day of submission by bacteria, fungi, viruses, requires the united sampling inspection. 6.2 test in Figure 1. Figure 1 test

7 Detection

According to the provisions of GB/T 14926.1 ~ 14926.64 be itemized.

8 detection rule

8.1 Frequency Detection 8.1.1 Common Animals. Animal least once every three months. 8.1.2 Cleaning Animals. Animal least once every three months. 8.1.3 Specific pathogen Animals. Animals detecting at least once every three months. 8.1.4 Sterile Animals. Animal once a year. Every 2-4 weeks check the animals living environment specimens and stool samples. 8.2 sampling requirements 8.2.1 adult animals should be selected for testing. 8.2.2 Number of Samples. Each mouse, rat, hamster, guinea pig and rabbit breeding production unit; and every dog, monkey breeding colony of production, according to The number of animals, the number of samples shown in Table 7. Table breeding different production units Number of Samples 7 animals Population size/sampling only a number < 100 100 to 500 > 500 Less than 5 Less than 10 Less than 20 a detector 2 each isolator. 8.3 sampling inspection 8.3.1 should be produced in different directions for each breeding unit (for example. four corners and center) to select animals. 8.3.2 animal inspection vessel shall animal level requirements and identification number, packaging, security service laboratory, together with the submission form, giving the animal Variety strain, grade, and the number of test items. 8.3.3 No specific requirements, rabbits, dogs and monkeys in vivo sampling in the production of reproductive unit. 8.4 classification test items 8.4.1 Test items must. refers to the quality of laboratory animals must be tested during the evaluation of the project. 8.4.2 necessary test items. refers to the introduction of animals from abroad; suspected of having the disease prevails; apply for production licenses and real experimental animals Laboratory animals must be detected when the quality certification of the project.

9 results found

In each grade animal testing and, if an index does not meet the grade requirements of standard indicators, the penalty for not complying with the standard grade. 10 of the report According to test results and issue reports.

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