GB/T 24776-2009 English PDF

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GB/T 24776-2009: Grouping and read-across methods of chemicals
Status: Valid

Standard ID	USD	BUY PDF	Lead-Days	Standard Title (Description)	Status
GB/T 24776-2009	229	Add to Cart	3 days	Grouping and read-across methods of chemicals	Valid

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Basic data

Standard ID: GB/T 24776-2009 (GB/T24776-2009)
Description (Translated English): Grouping and read-across methods of chemicals
Sector / Industry: National Standard (Recommended)
Classification of Chinese Standard: A80
Classification of International Standard: 13.300
Word Count Estimation: 10,165
Date of Issue: 2009-12-15
Date of Implementation: 2010-07-01
Regulation (derived from): Announcement of Newly Approved National Standards No. 15 of 2009
Issuing agency(ies): General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China, Standardization Administration of the People's Republic of China
Summary: This standard specifies the chemical substances used for grouping test data gaps and cross- reference data predicting chemical endpoints guide. This standard applies to the use of grouping and cross- reference predicting the end of chemical substances missing data.

GB/T 24776-2009: Grouping and read-across methods of chemicals

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Grouping and read-across methods of chemicals ICS 13.300 A80 National Standards of People's Republic of China Chemical grouping and cross-reference method Posted 2009-12-15 2010-07-01 implementation Administration of Quality Supervision, Inspection and Quarantine of People's Republic of China Standardization Administration of China released

Foreword

The standard reference of the United Nations' global chemical classification and labeling system "(GHS) and the first revision of the EU's" Chemicals Registration, Evaluation, Authorisation and Restriction "(REACH) Guidance Document 3.2" information requirements and chemical safety assessment "(in English), and the relevant technical content Said exactly the same file. The Standard Appendix A, Appendix B is an informative annex. This standard is managed by the National Standardization Technical Committee chemicals dangerous (SAC/TC251) and focal points. This standard is drafted by. AQSIQ's import and export of chemical safety research center. Participated in the drafting of this Standard. China Inspection and Quarantine Science Research Institute, the Chemical Institute of Standardization, Jiangsu CIQ, Shandong Entry-Exit Inspection and Quarantine of Jiangxi. The main drafters of this standard. Wang Lifeng, Falls Apart, Yu Wen Lin, Wang Xiaobing, Mei Jian, Zhou Xin, Sun Xin, Wang . This standard is the first release.

Introduction

EU on June 1, 2007 through the registration of chemicals legislation, evaluation, authorization and restriction regulations (hereinafter referred to as the REACH Regulation), And in 2008 June 1 formally implemented. After the implementation of the regulation of chemicals entering the EU market for unified management. Our country is Response to the EU REACH regulations, developed a series of chemical safety standards equivalent to the conversion of the relevant technical content EU REACH regulations. The standard reference of the United Nations' global chemical classification and labeling system "(GHS) and the first revision of the EU's" Chemicals Registration, Evaluation, Authorisation And Restriction "(REACH) Guidance Document 3.2" information requirements and chemical safety assessment "(in English), its content and the relevant technical Said exactly the same document, establish guidelines chemical grouping and cross-referenced. Chemical grouping and cross-reference method

1 Scope

This standard gives a chemical substance use grouping and cross-reference guide Prediction chemicals end data of the test data gaps. This standard applies to the use of grouping and cross-referencing method to predict the end of the data missing chemicals.

2 Terms and definitions

The following terms and definitions apply to this standard. 2.1 Further chemical same prediction method similar to the destination information to a structure based on endpoint information source chemicals. 2.2 A chemical class contains a similar structure or structural features of chemical substances, due to the structural similarities, their physicochemical Characteristics, health or environmental toxicity Toxicity Characteristic features also have certain similarities, or according to certain rules change. 2.3 Material effects and molecular descriptors (quantitative) the relationship between the characters. 2.4 Characterized satisfy structural similarity, chemical substances for cross-referencing the target chemical substance. 2.5 Missing end point data, need to be predicted chemicals. 2.6 When the target chemical substances prediction, referred chemicals. Heat 3 chemicals 3.1 Principle grouping Process chemicals group, that is, having a similar chemical structure, the same time as having a similar chemical structure or similar According to certain rules changes in the physical and chemical characteristics, health or environmental toxicity Toxicity Characteristic features of the process of a substance classified as chemical categories. will Chemicals grouped after, can on the basis of cross-referencing. Structural similarity 3.2 Structural similarity in the following areas. a) The chemical substance having the same functional groups (such as aldehydes, epoxides, esters, metal ionic species specific); b) each of the same chemical substance having the same component or classified as hazard class, having similar carbon chain length. This section mainly refers to Unknown or variable component substances, complex reaction products or biological material substance (UVCB); c) The chemicals in the structure (such as a carbon chain length) show an increasing or remain the same feature, this feature can be observed of Physical and chemical properties of chemical substances (such as boiling range) to give; ......

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