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GB/T 37272-2018 English PDF

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GB/T 37272-2018: Determination of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol in urine -- Liquid chromatography-tandem mass spectrometry method
Status: Valid
Standard IDUSDBUY PDFLead-DaysStandard Title (Description)Status
GB/T 37272-2018199 Add to Cart 3 days Determination of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol in urine -- Liquid chromatography-tandem mass spectrometry method Valid

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Basic data

Standard ID: GB/T 37272-2018 (GB/T37272-2018)
Description (Translated English): Determination of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol in urine -- Liquid chromatography-tandem mass spectrometry method
Sector / Industry: National Standard (Recommended)
Classification of Chinese Standard: C06
Classification of International Standard: 11.020
Word Count Estimation: 10,165
Date of Issue: 2018-12-28
Date of Implementation: 2019-04-01
Issuing agency(ies): State Administration for Market Regulation, China National Standardization Administration

GB/T 37272-2018: Determination of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol in urine -- Liquid chromatography-tandem mass spectrometry method


---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Determination of 11--nor--9--carboxy--delta--9--tetrahydrocannabinol in urine--Liquid chromatography--tandem mass spectrometry method ICS 11.020 C06 National Standards of People's Republic of China Determination of Δ9-tetrahydrocannamic acid in urine Liquid chromatography-tandem mass spectrometry Published on.2018-12-28 Implementation of.2019-04-01 State market supervision and administration China National Standardization Administration issued

Foreword

This standard was drafted in accordance with the rules given in GB/T 1.1-2009. This standard is proposed and managed by the Ministry of Justice of the People's Republic of China. This standard was drafted. Forensic Science Research Institute. The main drafters of this standard. Zhuo Xianyi, Xiang Ping, Liu Wei, Yan Hui, Shen Baohua, Ma Dong, Shi Wei, Shen Min. Determination of Δ9-tetrahydrocannamic acid in urine Liquid chromatography-tandem mass spectrometry

1 Scope

This standard specifies the liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for the determination of Δ9-tetrahydrocannamic acid in urine. This standard applies to the qualitative analysis and quantitative analysis of Δ9-tetrahydrocannamic acid in urine.

2 Normative references

The following documents are indispensable for the application of this document. For dated references, only dated versions apply to this article. Pieces. For undated references, the latest edition (including all amendments) applies to this document. GB/T 6682 Analytical laboratory water specifications and test methods GA/T 122 Toxic Analysis Terminology

3 Terms and definitions

The terms and definitions defined by GA/T 122 apply to this document.

4 Principle

In the urine, Δ9-tetrahydrocannanic acid is hydrolyzed under alkaline conditions, and then extracted under acidic conditions with an organic solvent, using liquid chromatography-tandem Mass spectrometry was performed.

5 reagents or materials

The reagents used are analytically pure reagents unless otherwise specified; water is primary water in accordance with GB/T 6682; reagents and materials include. a) n-hexane. b) Ethyl acetate. c) Acetonitrile. HPLC grade. d) Formic acid. excellent grade. e) Ammonium acetate. chromatographically pure. f) Glacial acetic acid. excellent grade pure. g) 20mmol/L ammonium acetate solution. Take 1.54g of ammonium acetate, put it in a 1000mL volumetric flask, add appropriate amount of water, add 2.0mL of formic acid, Add water to the mark and shake well. h) 1mol/L sodium hydroxide solution. Take 4.0g of sodium hydroxide and dissolve it with 100mL of water. i) 1mol/L hydrochloric acid solution. Take 20.8mL of concentrated hydrochloric acid and dilute to 250mL with water. j) Δ9-tetrahydrocannabinic acid reference solution. a commercially available 100 μg/mL methanol solution, stored in a freezer in a refrigerator. Save time is 12 months.
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