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GB/T 26517-2011 English PDF

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GB/T 26517-2011: Determination of 24 preservative in cosmetics -- High performance liquid chromatography method
Status: Valid
Standard IDUSDBUY PDFLead-DaysStandard Title (Description)Status
GB/T 26517-2011209 Add to Cart 3 days Determination of 24 preservative in cosmetics -- High performance liquid chromatography method Valid

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Basic data

Standard ID: GB/T 26517-2011 (GB/T26517-2011)
Description (Translated English): Determination of 24 preservative in cosmetics -- High performance liquid chromatography method
Sector / Industry: National Standard (Recommended)
Classification of Chinese Standard: Y42
Classification of International Standard: 71.100.70
Word Count Estimation: 9,928
Date of Issue: 2011-05-12
Date of Implementation: 2011-10-01
Quoted Standard: GB/T 6682
Regulation (derived from): Announcement of Newly Approved National Standards No. 6 of 2011
Issuing agency(ies): General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China, Standardization Administration of the People's Republic of China
Summary: This standard specifies the twenty-four kinds of preservatives in cosmetics by HPLC side given method. This standard applies to creams, lotions, lotions and other skin care cosmetics category twenty-four kinds of preservatives determination.

GB/T 26517-2011: Determination of 24 preservative in cosmetics -- High performance liquid chromatography method


---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Determination of 24 preservative in cosmetics. High performance liquid chromatography method ICS 71.100.70 Y42 National Standards of People's Republic of China Twenty-four kinds of preservatives in cosmetic determination High Performance Liquid Chromatography Issued on. 2011-05-12 2011-10-01 implementation Administration of Quality Supervision, Inspection and Quarantine of People's Republic of China Standardization Administration of China released

Foreword

The standard proposed by China National Light Industry Council. This standard by the National Standardization Technical Committee of Fragrance Flavor and Cosmetic (SAC/TC257) centralized. This standard was drafted. Chinese Academy of Inspection and Quarantine, the Shanghai Daily Chemical Industry Research Institute, Shanghai Institute of Spices, Shanghai Quality Inspection and Technical Research Institute. The main drafters of this standard. Wu Ting, Wang Chao, Ma Qiang, Xiao Haiqing, Zhang, Shen Min, Kang Wei. Twenty-four kinds of preservatives in cosmetic determination High Performance Liquid Chromatography

1 Scope

This standard specifies the cosmetics HPLC method twenty-four kinds of preservatives. This standard applies to creams, lotions, water, and other skin care cosmetics category twenty-four kinds of preservatives in cosmetic determination.

2 Normative references

The following documents contain provisions which, through reference in this standard and become the standard terms. For dated references, subsequent Amendments (not including errata content) or revisions do not apply to this standard, however, encourage the parties to the agreement are based on research Whether the latest versions of these documents. For undated reference documents, the latest versions apply to this standard. Laboratory use specifications and test methods GB/T 6682 Analysis Principle 3 Methanol as solvent, ultrasonic extraction, centrifugation, 0.45μm organic membrane filter, the solution was injected with a diode array detector (DAD) liquid chromatography detection, external standard.

4 Reagents and materials

Unless otherwise specified, reagents were of analytical grade. Water as a water GB/T 6682 regulations. 4.1 Methanol. chromatographically pure. 4.2 salicylic acid, purity of not less than 99.0%; ethyl 4-hydroxybenzoate, purity of not less than 99.0%; propyl 4-hydroxybenzoate, the purity is not Less than 99.0%; 4-hydroxybenzoic acid ester, a purity of not less than 99.0%; methyl 4-hydroxybenzoate, purity of not less than 99.0%; methyl isobutyl chloro Thiazolidinone, purity of not less than 99.0%; methylisothiazolinone, purity of not less than 99.0%; benzyl alcohol, purity of not less than 99.0%; phenoxy Ethanol, purity of not less than 99.0%; p- chloro -m- cresol, purity of not less than 98.0%; triclosan, purity of not less than 97.0%; triclocarban, A purity of not less than 99.0%; benzoate, a purity of not less than 99.0%; ethyl benzoate, purity of not less than 99.0%; phenyl benzoate, pure Not less than 99.0%; 2-bromo-2-nitropropane-1,3-diol, a purity of not less than 98.0%; 2,4-dichloro-3,5-dimethylphenol, purity of not less than 99.0%; 4-hydroxy benzoate, purity of not less than 99.0%; o- phenylphenol, purity of not less than 98.0%; chlorine xylenol, purity is not Less than 98.0%; 4-hydroxy benzoate, isobutyl purity of not less than 99.0%; benzyl chlorophenol, purity of not less than 99.0%; p purity not less To 99.0%; sorbic acid, purity of not less than 99.0%. Note. 2,4-dichloro-3,5-di-p-cresol are not included in the supervision Wei Fa [2007] No. 1 "Hygienic Standard for Cosmetics" Table 4 "cosmetic components restricted preservative" in. 4.3 preservative Standard stock solution. Accurately weigh each preservative (4.2) 0.5g, accurate to 0.0001g, were placed in 50mL beaker, add An appropriate amount of methanol dissolved and transferred to 100mL volumetric flask, diluted with methanol to the mark, mix, that was 5000mg/L of each standard stock preservative Preparation of liquid. 4.4 preservative mixed standard stock solution. Pipette are standard stock solution of 2mL (4.3) to 100mL volumetric flask with methanol to Scale, that was each preservative concentration was 100mg/L mixed standard stock solution. Preserve refrigerator can be used for three months. 4.5 Preservatives standard solution. methanol mixed standard stock solution (4.4) respectively dubbed a series of concentration of 0.5μg/mL, 1μg/mL, 5μg/mL, 10μg/mL, the standard working solution 20μg/mL, and stored in the refrigerator, may be used one week. 4.6 0.025mol/L sodium dihydrogen phosphate solution (pH3.80). Weigh sodium dihydrogen phosphate (NaH2PO4 · 2H2O) 3.9g, accurate to 0.001g, in a 50 mL beaker, dissolved in water and transferred to 1000 mL volumetric flask with water to volume, mix, that was
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