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GB/T 41683-2022 English PDF

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US$189.00 · In stock
Delivery: <= 3 days. True-PDF full-copy in English will be manually translated and delivered via email.
GB/T 41683-2022: Determination of prohibited colchicine and its derivative demecolcine in cosmetics - Liquid chromatography-tandem mass spectrometry
Status: Valid

Standard ID	USD	BUY PDF	Lead-Days	Standard Title (Description)	Status
GB/T 41683-2022	189	Add to Cart	3 days	Determination of prohibited colchicine and its derivative demecolcine in cosmetics - Liquid chromatography-tandem mass spectrometry	Valid

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Basic data

Standard ID: GB/T 41683-2022 (GB/T41683-2022)
Description (Translated English): Determination of prohibited colchicine and its derivative demecolcine in cosmetics - Liquid chromatography-tandem mass spectrometry
Sector / Industry: National Standard (Recommended)
Classification of Chinese Standard: Y42
Classification of International Standard: 71.100.70
Word Count Estimation: 10,154
Date of Issue: 2022-10-14
Date of Implementation: 2023-05-01
Issuing agency(ies): State Administration for Market Regulation, China National Standardization Administration

GB/T 41683-2022: Determination of prohibited colchicine and its derivative demecolcine in cosmetics - Liquid chromatography-tandem mass spectrometry

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Determination of prohibited colchicine and its derivative demecolcine in cosmetics -- Liquid chromatography-tandem mass spectrometry ICS 71.100.70 CCSY42 National Standards of People's Republic of China Prohibited Substances Colchicine and Its Derivatives in Cosmetics Determination of colchicamide by liquid chromatography-tandem mass spectrometry Published on 2022-10-12 2023-05-01 Implementation State Administration for Market Regulation Released by the National Standardization Administration

foreword

This document is in accordance with the provisions of GB/T 1.1-2020 "Guidelines for Standardization Work Part 1.Structure and Drafting Rules of Standardization Documents" drafted. Please note that some content of this document may be patented. The issuing agency of this document assumes no responsibility for identifying patents. This document is proposed by China National Light Industry Federation. This document is under the jurisdiction of the National Standardization Technical Committee of Fragrance, Flavor and Cosmetics (SAC/TC257). This document is drafted by. Shenzhen Customs Food Inspection and Quarantine Technology Center, Shenzhen Scientific Research Institute of Inspection and Quarantine. The main drafters of this document. Kang Haining, Shen Jincan, Zhao Fengjuan, Lin Weijian, Xu Tingting, Hua Honghui, Luo Yao, Chen Peijin, Xie Zhirong, Wu Zhangjie, Ruan Zijie, Li Yamei.

Introduction

The tested substances in this document are prohibited raw materials stipulated in my country's "Cosmetics Safety Technical Specifications (2015 Edition)". Prohibited raw materials refer to substances that cannot be used as cosmetic raw materials. "Cosmetics Safety Technical Specifications (2015 Edition)" stipulates that if the technical When it is unavoidable that the prohibited substances are brought into cosmetics as impurities, the limited amount stipulated by the state shall comply with its regulations; if the limit is not specified, the Safety risk assessment to ensure that there is no harm to human health under normal, reasonable and foreseeable conditions of use. At present, my country has not stipulated the limit values of these substances. The formulation of this document only provides detection methods for the determination of these substances in cosmetics. Prohibited Substances Colchicine and Its Derivatives in Cosmetics Determination of colchicamide by liquid chromatography-tandem mass spectrometry Caution - Persons using this document should have practical experience in formal laboratory work. This document does not address all possible security issues question. It is the user's responsibility to take appropriate safety and health measures and to ensure compliance with the relevant state regulations.

1 Scope

This document describes the method for the determination of colchicine and its derivative colchicamide, a prohibited substance in cosmetics, by liquid chromatography-tandem mass spectrometry. Principles, reagents and materials, instruments and equipment, test procedures, test data processing, recovery rate, precision, etc. This document applies to colchicine and its derivative colchicamide in water-based, lotion, cream, gel, wax-based, powder-based and other cosmetics. Determination. The detection limit and quantification limit of the method in this document. the detection limit of colchicine and colchicamide are both 5.0 μg/kg, and the quantification limit is 5.0 μg/kg. 10.0 μg/kg.

2 Normative references

The contents of the following documents constitute essential provisions of this document through normative references in the text. Among them, dated citations documents, only the version corresponding to that date applies to this document; for undated references, the latest edition (including all amendments) applies to this document. GB/T 6682 Analysis Laboratory Water Specifications and Test Methods

3 Terms and Definitions

There are no terms and definitions that need to be defined in this document.

4 Test methods

4.1 Principle After ultrasonic extraction and centrifugation of the extract, the samples were determined and characterized by liquid chromatography-tandem mass spectrometry, and quantified by external standard method. 4.2 Reagents and materials 4.2.1 Water. GB/T 6682, Class I. 4.2.2 Methanol. chromatographically pure. 4.2.3 Acetonitrile. chromatographically pure. 4.2.4 Absolute ethanol. chromatographically pure. 4.2.5 n-hexane. chromatographically pure. 4.2.6 Ammonium acetate. chromatographically pure. 4.2.7 Ammonium acetate. analytically pure. ......

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Tips & Frequently Asked Questions:

Question 1: How long will the true-PDF of GB/T 41683-2022_English be delivered?

Answer: Upon your order, we will start to translate GB/T 41683-2022_English as soon as possible, and keep you informed of the progress. The lead time is typically 1 ~ 3 working days. The lengthier the document the longer the lead time.

Question 2: Can I share the purchased PDF of GB/T 41683-2022_English with my colleagues?

Answer: Yes. The purchased PDF of GB/T 41683-2022_English will be deemed to be sold to your employer/organization who actually pays for it, including your colleagues and your employer's intranet.

Question 3: Does the price include tax/VAT?

Answer: Yes. Our tax invoice, downloaded/delivered in 9 seconds, includes all tax/VAT and complies with 100+ countries' tax regulations (tax exempted in 100+ countries) -- See Avoidance of Double Taxation Agreements (DTAs): List of DTAs signed between Singapore and 100+ countries

Question 4: Do you accept my currency other than USD?

Answer: Yes. If you need your currency to be printed on the invoice, please write an email to Sales@ChineseStandard.net. In 2 working-hours, we will create a special link for you to pay in any currencies. Otherwise, follow the normal steps: Add to Cart -- Checkout -- Select your currency to pay.