SN/T 3948-2014 English PDFUS$319.00 ยท In stock
Delivery: <= 3 days. True-PDF full-copy in English will be manually translated and delivered via email. SN/T 3948-2014: Chemical - In vitro skin irritation - Reconstructed human epidermis test method Status: Valid
Basic dataStandard ID: SN/T 3948-2014 (SN/T3948-2014)Description (Translated English): Chemical - In vitro skin irritation - Reconstructed human epidermis test method Sector / Industry: Commodity Inspection Standard (Recommended) Classification of Chinese Standard: G09 Classification of International Standard: 13.300 Word Count Estimation: 12,122 Date of Issue: 4/9/2014 Date of Implementation: 11/1/2014 Quoted Standard: GB/T 27830-2011 Regulation (derived from): State inspection certification (2014) 210 Issuing agency(ies): General Administration of Customs Summary: This standard specifies the principles of testing chemicals in vitro human epidermal skin irritation test, the test procedure and data and reports. This standard applies to the United Nations Globally Harmonized System of Classification and Labelling (ref SN/T 3948-2014: Chemical - In vitro skin irritation - Reconstructed human epidermis test method---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.(Chemicals in vitro skin irritation. Recombinant Human Epidermal test) People's Republic of China Entry-Exit Inspection and Quarantine Standards Chemicals in vitro skin irritation. Recombinant human epidermal test Issued on. 2014-04-09 2014-11-01 implementation People's Republic of China The State Administration of Quality Supervision, Inspection and Quarantine released ForewordThis standard was drafted in accordance with GB/T 1.1-2009 given rules. This standard technical content and Organisation for Economic Co-operation and Development (OECD) Chemicals Test Method 439 "In Vitro Skin Irritation. recombinant human form Intradermal test "(Invitroskinirritation. reconstructedhumanepidermistestmethod) (2010) The content of the. This standard is proposed and managed by the National Certification and Accreditation Administration Committee. This standard was drafted. People's Republic of China Shanghai Entry-Exit Inspection and Quarantine Bureau. The main drafters of this standard. Yao Lifang, Taohai Hua, Li Ning, Miao Wenbin Jiang Wei, Li Wei, Zhu Hongkun, Qing Zhao Yi, Zheng Hua. Chemicals in vitro skin irritation. Recombinant human epidermal test1 ScopeThis standard specifies the principles of testing chemicals in vitro human epidermal skin irritation test, the test procedure and data and reports. This standard applies to the United Nations Globally Harmonized System of Classification and Labelling (referred to as the GHS) and the European Union classify substances and mixtures, labeling And Packaging Regulation (called CLP) Category 2 irritant chemicals (chemical irritants) classification assessment. This standard does not apply to UN GHS Category 3 (mild irritant) classification assessment.2 Normative referencesThe following documents for the application of this document is essential. For dated references, only the dated version suitable for use herein Member. For undated references, the latest edition (including any amendments) applies to this document. Human skin model test method GB/T 27830-2011 chemicals vitro skin corrosion3 Terms and DefinitionsGB/T 27830-2011 define the following terms and definitions apply to the text element. 3.1 Cell activity celviability Index measuring overall cell population viability [e.g. mitochondrial dehydrogenase reducing activity tetrazolium dye (3- (4,5-dimethyl-thiazol-2) - 2,5-diphenyl tetrazolium bromide, MTT) (CASN o.298-93-1) capacity], depending on the endpoint measured and the indicators used in the design Program, and with the total number of cells and/or the number of active cells. [GB/T 27830-2011, Definition 2.2] 3.2 The median effective time medianeffectivetime; ET50 Given concentration, resulting in decreased cell viability by 50% the time required. 3.3 IC50 halfmaximalinhibitoryconcentration; IC50 Under certain exposure time, the concentration of cells resulting in reduced activity by 50%. 3.4 Skin irritation skinirritation 4h after contact with the test substance, causing irreversible damage skin. Skin irritation is a local non-immunogenic reaction, stimulated After a short time it will happen. The main features are reversible, including inflammation and irritation associated with the inflammation process of clinical symptoms (red Plaques, edema, itching and pain). 3.5 Optical density opticaldensity; OD The ratio of the intensity of incident light and the transmitted light intensity of the common logarithm. It represents the optical density of the absorption of the test substance. A specific wavelength, with One kind is the concentration of the test object and the energy is absorbed into the quantitative relationship. ......Tips & Frequently Asked Questions:Question 1: How long will the true-PDF of SN/T 3948-2014_English be delivered?Answer: Upon your order, we will start to translate SN/T 3948-2014_English as soon as possible, and keep you informed of the progress. The lead time is typically 1 ~ 3 working days. The lengthier the document the longer the lead time.Question 2: Can I share the purchased PDF of SN/T 3948-2014_English with my colleagues?Answer: Yes. The purchased PDF of SN/T 3948-2014_English will be deemed to be sold to your employer/organization who actually pays for it, including your colleagues and your employer's intranet.Question 3: Does the price include tax/VAT?Answer: Yes. 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