GBZ60-2014 English PDFUS$169.00 · In stock
Delivery: <= 3 days. True-PDF full-copy in English will be manually translated and delivered via email. GBZ60-2014: Diagnosis of occupational hypersensitivity pneumonitis Status: Valid GBZ60: Historical versions
Basic dataStandard ID: GBZ 60-2014 (GBZ60-2014)Description (Translated English): Diagnosis of occupational hypersensitivity pneumonitis Sector / Industry: National Standard Classification of Chinese Standard: C60 Classification of International Standard: 13.100 Word Count Estimation: 7,759 Date of Issue: 10/13/2014 Date of Implementation: 3/1/2015 Older Standard (superseded by this standard): GBZ 60-2002 Quoted Standard: GB/T 16180 Regulation (derived from): State-Health-Communication [2014] 14 Issuing agency(ies): National Health and Family Planning Commission Summary: This standard specifies the principles of diagnosis of occupational hypersensitivity pneumonitis, contact reaction, diagnosis and treatment principles. This standard applies to the diagnosis and treatment of occupational activities through contact with bi GBZ60-2002: Diagnostic Criteria of Occupational Acute Allergic Alveolitis---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.Diagnostic Criteria of Occupational Acute Allergic Alveolitis ICS 13.100 C60 GBZ People's Republic of China National Occupational Health Standards Diagnostic criteria for occupational acute allergic alveolitis Released in.2002-04-08 2002-06-01 Implementation Issued by the Ministry of Health of the People's Republic of China ForewordArticle 5.1 of this standard is recommended and the remainder is mandatory. According to the "People's Republic of China Occupational Disease Prevention Law" to develop this standard. Since the implementation of the standard date, the original standard GB 16380-1996 inconsistent with this standard, subject to this standard. In contact with mold, bacteria or other protein organic dust in the professional activities, can cause changes in alveolar allergic reaction Acute alveolitis. In order to be able to diagnose and correctly handle, to protect the health of the operator, the development of this standard. Appendix A to this standard is an informative appendix and Appendix B is a normative appendix. This standard is proposed and centralized by the Ministry of Health of the People's Republic of China. This standard is drafted by Fushan University Huashan Hospital and Guangdong Provincial Occupational Disease Prevention and Control Institute. This standard is interpreted by the Ministry of Health of the People's Republic of China. Diagnostic criteria for occupational acute allergic alveolitis Occupational acute allergic alveolitis is caused by the inhalation of some organic dust with antigenicity in the production process Alveolar allergic changes in the main respiratory diseases.1 ScopeThis standard specifies the diagnostic criteria and principles of occupational acute allergic alveolitis. This standard applies to acute alveolitis after exposure to mold, bacteria or other protein organic dust. Such as farmers Lung, bagasse lung, humidifier and other acute patients in the diagnosis and treatment.2 diagnostic principlesAccording to a clear re-inhalation of allergenic occupational history, after a certain incubation period after the respiratory system-based clinical Symptoms, signs and chest X-ray performance, combined with on-site hygiene survey results, reference to lung function, arterial blood gas and serum Precipitated antibody determination results, excluding other causes of similar lesions, a comprehensive analysis, can be diagnosed.3 contact reactionInhalation of allergen 4 ~ 8h after the emergence of chills, fever, cough, chest tightness, shortness of breath, chest X-ray examination no lung Qualitative change. The above symptoms can subside within 1 week of disengagement. Diagnostic and grading standards 4.1 mild There are moderate and severe cough, accompanied by chest tightness, shortness of breath, chills, fever; two lungs can be heard and twisted pronunciation; chest X-ray In addition to double lung texture enhancement, and 1 ~ 5 mm size of the edge blurred, low density point-like shadow, the lesion range is not More than 2 lung areas; serum precipitation reaction can be positive. 4.2 Severe The above clinical manifestations increased, weight loss, fatigue; chest twist pronunciation increased; chest showed a patchy shadow, distribution Range more than 2 lung areas, or fuse into large blurred shadows. Serum precipitation reaction can be positive.5 Principles of handling5.1 Principles of treatment 5.1.1 contact with the reaction should be temporarily out of the scene, the necessary inspection and treatment, and close observation of 24 ~ 72 h. 5.1.2 mild should be temporarily out of the production environment to rest, and given cough, asthma, oxygen and other symptomatic treatment and the amount of glucocorticoid Hormone therapy. Pay attention to follow-up. 5.1.3 severe should be bed rest, early enough to use glucocorticoid and symptomatic treatment. 5.2 Other processing Mild who can be cured after the resumption of work, if the resumption of work after the short term and repeated attacks and those who should be removed from the The original job, and according to the degree of recovery, arrangements for appropriate work.6 Correct use of the description of this standardSee Appendix A (informative), Appendix B (normative).Appendix A(Informative) Correctly use the instructions in this standard A.1 This standard is only suitable for the diagnosis and treatment of acute patients such as peasant lung, bagasse fungus spores, mushroom lungs and so on. A.2 for patients with cyanosis or to be diagnosed with severe arterial blood gas analysis. A.3 serum-specific precipitated antibody positive results and dynamic changes contribute to the diagnosis, but negative also do not negate the diagnosis. A.4 Cough condition criteria. Mild (+). intermittent cough during the day, does not affect the normal life and work. Moderate (++). Symptoms are between mild (+) and severe (+++). Severe (+++). frequent cough or cough day and night, affecting work and sleep.Appendix B(Normative appendix) Two - way Immune Diffusion Test of Serum Precipitated Antibody B.1 Purpose Occupational acute allergic alveolitis pathogenesis mainly involves type Ⅲ allergy. In patients or related pathogens The specific antibody corresponding to the pathogen antigen can often be detected in the blood of the contact person. Therefore, serum precipitated antibody detection was performed Help to diagnose the etiology of patients. Principle B.2 The soluble antigens and antibodies were added to the corresponding wells in the agar plates, respectively, and the two were diffused around each other. The original and the antibody is the corresponding, then the proportion of the two can be formed in the white precipitation line. When the test substance contains more than one Of the antigen, the antibody system, due to the different diffusion coefficient of different antigens, the pair of antigens, the best proportion between the different antibodies, After the diffusion can be formed in different areas of a number of precipitation lines, and according to the adjacent two precipitation lines of the graphics are connected or cross, Know whether the two antigens belong to the same nature, so you can use this test to check the antigen or antibody purity. As well as with known resistance The original (or antibody) detects and analyzes unknown antibodies (or antigens). As the serum bacteria in the bacteria content is usually low, using the general Ouchterlony method positive detection rate is low, the The improved bi-directional diffusion method can improve the sensitivity of the reaction by nearly 10 times, and has high specificity. B.3 Materials B.3.1 Subjects were all serum. B.3.2 Known antigens. Select the relevant pathogen antigens, such as thermophilic actinomycetes, Streptomyces soluble Antigens or soluble antigenic substances extracted from production environment samples (eg, mold compost). B.3.3 Chemical reagents a) pH 7.5 boric acid buffer. Boric acid 2.48 g NaCl 6.96 g sodium borate 0.955 g Citric acid 10 g NaOH 3.5 g deionized water 1000 mL b) agarose (for electrophoresis); c) 1% phenol. B3.4 Other equipment a) 70 min × 60 mm slides; b) metal perforators with outer diameters of 5 mm and 11 mm; c) large injection needle, thin mouth straw. B.4 Procedure B.4.1 boric acid buffer 100 mL plus agarose 0.8 g, heated and melted and mixed, poured on a glass plate, the thickness of 2 mrn, Each about 8.4mL. B.4.2 After agarose is cooled, it is marked with a punch into a series of holes, which may be plum blossom or triangular (see Fig. B1). big hole Diameter 11 mm, small diameter 5 mm, double margin 5 mm. The agar in the hole was picked out with an injection needle and the residual agar in the hole was removed Suck out with a straw. Punch should be careful not to make the bottom of the agar and glass between the bubble, pay attention to the back cover. B.4.3 Add the serum to be measured in the macrowell, add the known antigen in the hole, and add it to the orifice. The above-mentioned double-plate was placed in a wet box containing 1% phenol and placed at room temperature (25 ° C) for 24 to 72 hours. If necessary, can be observed for dyeing, or dry film made of long-term preservation. B.5 Results to determine Antigens and antibodies (serum) are diffused, and if a white precipitate line is formed, a positive result is determined (see Map). A, B means that two samples of serum can be measured on a plate. 1 ~ 6. different antigen number, that is, a serum can be used to determine the six kinds of antigens. A, B can be shared 1,2 two Antigen. Determination of the actual needs, according to the use of different sizes of glass, a hole in the board can also be arranged according to the spacing And the principle of aperture design. ......Tips & Frequently Asked Questions:Question 1: How long will the true-PDF of GBZ60-2014_English be delivered?Answer: Upon your order, we will start to translate GBZ60-2014_English as soon as possible, and keep you informed of the progress. The lead time is typically 1 ~ 3 working days. The lengthier the document the longer the lead time.Question 2: Can I share the purchased PDF of GBZ60-2014_English with my colleagues?Answer: Yes. 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