GBZ39502-2020 English PDF

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GBZ39502-2020: Laboratory animal - Guideline of COVID-19 animal models preparation
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Standard ID	USD	BUY PDF	Lead-Days	Standard Title (Description)	Status
GB/Z 39502-2020	119	Add to Cart	3 days	Laboratory animal - Guideline of COVID-19 animal models preparation	Valid

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Basic data

Standard ID: GB/Z 39502-2020 (GB/Z39502-2020)
Description (Translated English): Laboratory animal - Guideline of COVID-19 animal models preparation
Sector / Industry: National Standard
Classification of Chinese Standard: B44
Classification of International Standard: 65.020.30
Word Count Estimation: 6,653
Date of Issue: 2020-11-19
Date of Implementation: 2021-06-01
Regulation (derived from): National Standard Announcement No. 26 of 2020
Issuing agency(ies): State Administration for Market Regulation, China National Standardization Administration

GBZ39502-2020: Laboratory animal - Guideline of COVID-19 animal models preparation

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
GB /Z 39502-2020 Laboratory animal-Guideline of COVID-19 animal models preparation ICS 65.020.30 B44 National Standardization Guiding Technical Documents of the People's Republic of China Experimental animal novel coronavirus pneumonia (COVID-19) Animal Model Preparation Guide 2020-11-19 released 2021-06-01 implementation State Administration for Market Regulation Issued by the National Standardization Management Committee

Foreword

This guiding technical document was drafted in accordance with the rules given in GB/T 1.1-2009. This guiding technical document was proposed and managed by the National Laboratory Animal Standardization Technical Committee (SAC/TC281). Drafting units of this guiding technical document. Institute of Medical Laboratory Animals, Chinese Academy of Medical Sciences, Wuhan Institute of Virology, Chinese Academy of Sciences, Institute of Medical Biology, Chinese Academy of Medical Sciences, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences. The main drafters of this guiding technical document. Qin Chuan, Wei Qiang, Yuan Zhiming, Peng Xiaozhong, Bu Zhigao, Bao Linlin, Gao Hong, Deng Wei, Liu Jiangning, Kong Qi. Experimental animal novel coronavirus pneumonia (COVID-19) Animal Model Preparation Guide Important note. The animal model preparation and experimental process in this document require exposure to the new coronavirus, and operators should control the infection risk based on the risk assessment.

1 Scope

This technical guidance document provides guidance on the preparation principles, preparation methods and evaluation indicators of animal models of novel coronavirus pneumonia (COVID-19). This technical guidance document is applicable to the preparation and evaluation of animal models of novel coronavirus pneumonia (COVID-19).

2 Normative references

The following documents are indispensable for the application of this document. For dated reference documents, only the dated version applies to this document. For undated references, the latest version (including all amendments) applies to this document. GB 14925-2010 Laboratory Animal Environment and Facilities GB 19489-2008 General requirements for laboratory biosafety GB/T 35892 Guidelines for Ethical Review of Laboratory Animal Welfare

3 Terms and definitions

The following terms and definitions apply to this document. 3.1 Novel Coronavirus Pneumonia (COVID-19) Animal Model Artificially infect animals with the new coronavirus (SARS-CoV-2) strain, so that it can simulate the clinical manifestations and onset of COVID-19 Disease animals with characteristics such as process, pathophysiological changes, immunological response, etc.

4 Preparation principles

4.1 Choose susceptible animals It should be based on the animal's breed, genetic classification, microbiological grade, and sensitivity to the new coronavirus (SARS-CoV-2), etc. Choose experimental animals. 4.2 Selection of representative pathogens According to the clinical epidemiological data of human COVID-19 and the experimental purpose of the animal model, select the relevant pathogenic representative strains and fill them. Consider the active state of the pathogen. 4.3 Maximizing disease reproduction When preparing the COVID-19 animal model, it simulates the clinical manifestations, disease process, and pathophysiology of human COVID-19 disease to the greatest extent ......

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