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GB/T 40896-2021 English PDF

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GB/T 40896-2021: Determination of diethylene glycol monoethyl ether in cosmetics - Gas chromatography mass spectrometry
Status: Valid
Standard IDUSDBUY PDFLead-DaysStandard Title (Description)Status
GB/T 40896-2021179 Add to Cart 3 days Determination of diethylene glycol monoethyl ether in cosmetics - Gas chromatography mass spectrometry Valid

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Basic data

Standard ID: GB/T 40896-2021 (GB/T40896-2021)
Description (Translated English): Determination of diethylene glycol monoethyl ether in cosmetics - Gas chromatography mass spectrometry
Sector / Industry: National Standard (Recommended)
Classification of Chinese Standard: Y42
Word Count Estimation: 9,933
Issuing agency(ies): State Administration for Market Regulation, China National Standardization Administration

GB/T 40896-2021: Determination of diethylene glycol monoethyl ether in cosmetics - Gas chromatography mass spectrometry


---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Determination of diethylene glycol monoethyl ether in cosmetics - Gas chromatography mass spectrometry ICS 71.100.70 CCSY42 National Standards of People's Republic of China Determination of diethylene glycol monoethyl ether in cosmetics Gas chromatography-mass spectrometry Released on 2021-11-26 2022-06-01 implementation State Administration for Market Regulation Issued by the National Standardization Management Committee

Foreword

This document is in accordance with the provisions of GB/T 1.1-2020 "Guidelines for Standardization Work Part 1.Structure and Drafting Rules of Standardization Documents" Drafting. Please note that some of the contents of this document may involve patents. The issuing agency of this document is not responsible for identifying patents. This document was proposed by the China National Light Industry Council. This document is under the jurisdiction of the National Standardization Technical Committee for Fragrance, Flavor and Cosmetics (SAC/TC257). Drafting organizations of this document. China Academy of Inspection and Quarantine Sciences, Shanghai Perfume Research Institute. The main drafters of this document. Chen Meng, Ma Qiang, Li Wentao, Zong Yijing, Shang Yuhan, Bai Hua.

Introduction

The tested substance diethylene glycol monoethyl ether in this document and the banned raw material B stipulated in my country's "Safety Technical Specifications for Cosmetics (2015 Edition)" Glycol dimethyl ether, ethylene glycol methyl ether, ethylene glycol ethyl ether, ethylene glycol methyl ether acetate, ethylene glycol ethyl ether acetate, diethylene glycol methyl ether, triethylene glycol Dimethyl ether is also a glycol ether compound with similar properties and structure. At present, my country has not yet stipulated the limit value of diethylene glycol monoethyl ether. The formulation of this document only provides testing for the determination of this substance in cosmetics. method. Determination of diethylene glycol monoethyl ether in cosmetics Gas chromatography-mass spectrometry Warning---Personnel using this document should have practical experience in formal laboratory work. This document does not indicate all possible safety issues The user is responsible for taking appropriate safety and health measures and ensuring compliance with the conditions stipulated by relevant national laws and regulations.

1 Scope

This document describes the principles, reagents and materials, instruments and equipment of the gas chromatography-mass spectrometry method for the determination of diethylene glycol monoethyl ether in cosmetics Test procedures, test data processing, recovery rate, precision, etc. This document is applicable to the determination of diethylene glycol monoethyl ether in liquid, emulsion, cream and spray cosmetics. The detection limit of the method in this document is 0.25mg/kg, and the limit of quantification is 0.50mg/kg.

2 Normative references

The content of the following documents constitutes an indispensable clause of this document through normative references in the text. Among them, dated quotations Only the version corresponding to the date is applicable to this document; for undated reference documents, the latest version (including all amendments) is applicable to This document. GB/T 6682 Analytical laboratory water specifications and test methods

3 Terms and definitions

There are no terms and definitions that need to be defined in this document.

4 Principle

After the sample is extracted by solvent, the extract is centrifuged, dehydrated, filtered, and determined by gas chromatography-mass spectrometer, and quantified by external standard method.

5 Reagents and materials

Unless otherwise specified, all reagents used are of analytical grade. 5.1 Water, GB/T 6682, level one. 5.2 Methanol. chromatographically pure. 5.3 Sodium chloride. the content is not less than 99.8%. 5.4 Anhydrous sodium sulfate. burn it at 650°C for 4h and place it in a desiccator. 5.5 Diethylene glycol monoethyl ether standard substance. molecular formula is C6H14O3, CAS number is 111-90-0, purity is 99.5%, chemical structure formula is attached Record A in Figure A.1. 5.6 Diethylene glycol monoethyl ether standard stock solution. accurately weigh 0.01g diethylene glycol monoethyl ether standard substance (5.5), accurate to 0.0001g, use Methanol (5.2) is formulated into a standard stock solution with a mass concentration of 100μg/mL, stored at 4°C and protected from light, and the validity period is 3 months. 5.7 Teflon plastic centrifuge tube with stopper. 15mL. 5.8 Microporous membrane. pore size 0.45μm, organic phase.
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