GB/T 15670.7-2017 English PDF

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GB/T 15670.7-2017: Toxicological test methods for pesticides registration -- Part 7: Dermal irritation/corrosion test
Status: Valid

Standard ID	USD	BUY PDF	Lead-Days	Standard Title (Description)	Status
GB/T 15670.7-2017	119	Add to Cart	3 days	Toxicological test methods for pesticides registration -- Part 7: Dermal irritation/corrosion test	Valid

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GB/T 15670.3   GB/T 15670.25   GB/T 15670.5   GB/T 15670.1   GB/T 15670.12   GB/T 15670.11   

Basic data

Standard ID: GB/T 15670.7-2017 (GB/T15670.7-2017)
Description (Translated English): Toxicological test methods for pesticides registration -- Part 7: Dermal irritation/corrosion test
Sector / Industry: National Standard (Recommended)
Classification of Chinese Standard: B17
Classification of International Standard: 65.100
Word Count Estimation: 6,657
Date of Issue: 2017-07-12
Date of Implementation: 2018-02-01
Regulation (derived from): s Republic of China
Issuing agency(ies): General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China, Standardization Administration of the People's Republic of China

GB/T 15670.7-2017: Toxicological test methods for pesticides registration -- Part 7: Dermal irritation/corrosion test

---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.
Toxicological test methods for pesticides registration - Part 7. Dermal irritation/corrosion test ICS 65.100 B17 National Standards of People's Republic of China Part of the replacement GB/T 15670-1995 Pesticide registration toxicology test method Part 7. skin irritation/corrosivity test Part 7. Dermalirritation/corrosiontest 2017-07-12 released 2018-02-01 Implementation General Administration of Quality Supervision, Inspection and Quarantine of the People 's Republic of China China National Standardization Management Committee released

Foreword

GB/T 15670 "Pesticide registration toxicology test method" is divided into the following parts. - Part 1. General; - Part 2. Acute oral toxicity test; - Part 3. Sequential method of acute oral toxicity test; - Part 4. Acute oral toxicity test probability unit method; - Part 5. Acute percutaneous toxicity test; - Part 6. Acute inhalation toxicity test; - Part 7. Skin irritation/corrosivity test; - Part 8. Acute eye irritation/corrosivity test; - Part 9. Skin allergy (sensitization) test; - Part 10. Short-term repeated oral exposure (28 days) toxicity test; - Part 11. Short term repeated percutaneous exposure (28 days) toxicity test; - Part 12. Short-term repeated inhalation exposure (28 days) toxicity test; - Part 13. Subchronic toxicity test; - Part 14. Bacterial response mutations; - Part 15. Micronucleus test of mammalian bone marrow polychromatic erythrocytes; - Part 16. Chromosome aberration test of mammalian bone marrow cells in vivo; - Part 17. Chromosome aberration of spermatogonia/spermatocytes in mammals; - Part 18. Sexual lethal test of rodents; - Part 19. In vitro mammalian cell chromosome aberration test; - Part 20. In vitro mammalian cell gene mutation test; Part 21. Systemic DNA synthesis (UDS) test for mammalian hepatocytes in vivo; - Part 22. DNA damage and repair/programmed DNA synthesis in mammalian cells in vitro; - Part 23. Teratogenic tests; - Part 24. Two generations of reproductive toxicity tests; - Part 25. Acute delayed neurotoxicity test; - Part 26. Chronic toxicity test; - Part 27. Cancer test; - Part 28. Chronic toxicity and carcinogenesis trials; - Part 29. Metabolic and toxic kinetic tests. This part is part 7 of GB/T 15670. This part is drafted in accordance with the rules given in GB/T 1.1-2009. This part of the part of GB/T 15670-1995 "pesticide registration toxicology test method". This part of the GB/T 15670-1995 compared with the acute skin irritation test part of the main changes are as follows. - to modify and adjust the overall structure of the standard and the format of the arrangement; - Added chapters (see Chapter 1, Chapter 2, Chapter 3, Chapter 5, 6.1, 6.2.2, 6.3.2, Chapter 7, Chapter 8); - modified the number of experimental animals (see 6.2.1), 5.3.2 of.1995; - Increased number of skin irritation tests (see 6.3.2); - modified skin irritation score, increased skin corrosion (see Table 1,.1995 edition of Table 4); - Improved skin irritation grade, increased skin corrosion (see Table 2,.1995, Table 5). This section is made by the Ministry of Agriculture of the People's Republic of China. This part is headed by the Department of Agriculture and Plant Management of the People's Republic of China. This part of the drafting unit. Ministry of Agriculture Pesticide Testing Institute. This part of the main drafters. Qin Yuhui, Qu 甍 甍, Zhang Liying, Tao Chuanjiang. This part of the previous version of the standard to replace the release of the situation. --- GB/T 15670-1995. Pesticide registration toxicology test method Part 7. skin irritation/corrosivity test

1 Scope

This part of GB/T 15670 specifies the basic principles, methods and requirements for skin irritation/corrosivity testing. This section applies to skin irritation/corrosivity tests for pesticide registration.

2 normative reference documents

The following documents are indispensable for the application of this document. For dated references, only the dated edition applies to this article Pieces. For undated references, the latest edition (including all modifications) applies to this document. Laboratory Animal Environment and Facilities

3 terms and definitions

The following terms and definitions apply to this document. 3.1 Skin irritation dermalirritation A reversible inflammatory change that occurs locally after application of the skin. 3.2 Skin corrosive dermalcorrosion An irreversible tissue injury that occurs locally after application of the skin.

4 Purpose of the test

Determine and evaluate whether the test substance has a stimulating or corrosive effect on the skin of the mammal and its extent.

5 Test Overview

Including acute skin irritation tests and multiple skin irritation tests. In the acute skin irritation test, the test substance is applied once On the skin of the tested animals, the degree of local irritation of the animal's skin was observed and scored at a prescribed time interval, To evaluate the effect of the test substance on the skin, the observation period should be sufficient to evaluate the reversibility or irreversibility of the effect; multiple skin irritation Sex test is in 14d, every day in the animal skin smear once the subject, according to the skin reaction score, determine the repeated exposure of the thorn Excitement.

6 test method

6.1 Test substance The liquid test substance is generally free from dilution and is used directly. The solid test substance should be ground into fine powder and water or other non-irritating ......

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