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Delivery: <= 6 days. True-PDF full-copy in English will be manually translated and delivered via email. GB 14923-2022: Laboratory animal - Genetic quality control Status: Valid GB 14923: Historical versions
Basic dataStandard ID: GB 14923-2022 (GB14923-2022)Description (Translated English): Laboratory animal - Genetic quality control Sector / Industry: National Standard Classification of Chinese Standard: B44 Classification of International Standard: 65.020.30 Word Count Estimation: 30,379 Date of Issue: 2022-12-29 Date of Implementation: 2023-07-01 Older Standard (superseded by this standard): GB 14923-2010 Issuing agency(ies): State Administration for Market Regulation, China National Standardization Administration GB 14923-2022: Laboratory animal - Genetic quality control---This is a DRAFT version for illustration, not a final translation. Full copy of true-PDF in English version (including equations, symbols, images, flow-chart, tables, and figures etc.) will be manually/carefully translated upon your order.ICS 65.020.30 CCSB44 National Standards of People's Republic of China Replacing GB 14923-2010 Laboratory Animal Genetic Quality Control Released on 2022-12-29 2023-07-01 implementation State Administration for Market Regulation Released by the National Standardization Management Committee forewordThis document is in accordance with the provisions of GB/T 1.1-2020 "Guidelines for Standardization Work Part 1.Structure and Drafting Rules for Standardization Documents" drafting. This document replaces GB 14923-2010 "Genetic Quality Control of Laboratory Animals and Mammalian Animals", and GB 14923-2010 In comparison, except for structural adjustments and editorial changes, the main technical changes are as follows. a) Changed the definitions of the terms "outly related group" and "closed group" (see 3.12, 3.13, 2.12 of the.2010 edition); b) Added the nomenclature for the preparation of genetically modified animals using technologies such as CRISPR/Cas9 (see 4.2.1.11); c) Added microsatellite and SNP locus detection method (see 6.2.3). Please note that some contents of this document may refer to patents. The issuing agency of this document assumes no responsibility for identifying patents. This document is proposed and managed by the Ministry of Science and Technology of the People's Republic of China. The release status of previous versions of this document and the documents it replaces are as follows. ---First published as GB 14923-1994 in.1994, first revised in.2010; --- This is the second revision. Laboratory Animal Genetic Quality Control1 ScopeThis document gives the genetic classification and nomenclature of experimental animals, breeding methods, and the genetic quality of animals in inbred lines, outbred groups, and hybrid groups. monitor. This document is applicable to the genetic quality control of experimental animals.2 Normative referencesThis document has no normative references.3 Terms and DefinitionsThe following terms and definitions apply to this document. 3.1 inbred strain inbredstrain In an animal population, more than 98.6% of the loci in any individual genome are homozygous strains. Note. Classical inbred lines are bred by mating full-siblings for at least 20 consecutive generations. All individuals in the line can be traced back to the 20th generation or later Algebraic pair of common ancestors. After more than 20 consecutive generations, parent-child mating has the same effect as full-sibling mating. inbreeding coefficient 3.2 Substrain substrain Branches within the inbred line. Note. There are differences between animals of each branch due to genetic differentiation. 3.3 After crossing two inbred lines, the inbred line is bred through more than 20 consecutive generations of brother-sister mating. 3.4 After crossing two inbred lines, the progeny is backcrossed with one of the two parental inbred lines several times (usually 2 times), and then passed through the wrong special Inbred lines bred by continuous brother-sister mating (usually more than 14 generations) selected by special genes. 3.5 Except for the alleles of a specific locus, two inbred lines with the same genetic genes. Note. It is generally formed by gene mutation or artificial mutagenesis (such as gene knockout) in inbred lines. Use inbreeding algebra to represent the algebra of mutation, such as F110 F23 means that the inbred line was inbred for 23 generations after the mutation appeared in the 110th generation. 3.6 congenicstrain Congener A specific marker is selected from the donor line, and an inbred line formed by backcrossing is only in a small chromosome segment ......Tips & Frequently Asked Questions:Question 1: How long will the true-PDF of GB 14923-2022_English be delivered?Answer: Upon your order, we will start to translate GB 14923-2022_English as soon as possible, and keep you informed of the progress. The lead time is typically 4 ~ 6 working days. The lengthier the document the longer the lead time.Question 2: Can I share the purchased PDF of GB 14923-2022_English with my colleagues?Answer: Yes. 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Unless special scenarios such as technical constraints or academic study, you should always prioritize to purchase the latest version GB 14923-2022 even if the enforcement date is in future. Complying with the latest version means that, by default, it also complies with all the earlier versions, technically. |
